{"id":"W1973561492","doi":"10.1371/journal.pone.0071336","title":"Interleukin-10 Inhibits Lipopolysaccharide Induced miR-155 Precursor Stability and Maturation","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research","keywords":"miR-155; Lipopolysaccharide; microRNA; Cell biology; Transcription factor; Cytokine; STAT3; Regulation of gene expression; Suppressor of cytokine signaling 1; Gene expression; Interleukin 6; Chemistry; Biology; Signal transduction; Immunology; Gene; Genetics; Suppressor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002126202,0.000282305,0.0002169582,0.0001565545,0.00008747522,0.0002422702,0.0001804456,0.0002277786,0.001997208],"category_scores_gemma":[0.0002373724,0.0001413837,0.0002670285,0.00007030179,0.0002139363,0.0001160854,0.0001743348,0.0006697055,0.0008001679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002283947,"about_ca_system_score_gemma":0.0003397895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004061449,"about_ca_topic_score_gemma":0.0007276002,"domain_scores_codex":[0.9998319,0.00004098241,0.00002241889,0.00002272312,0.00003113507,0.00005083419],"domain_scores_gemma":[0.9998521,0.00004179044,0.00002939845,0.00002023519,0.00001860061,0.00003789397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004873895,0.0001035045,0.0001255525,0.00007279785,0.000006552068,0.0000472664,0.00001632124,0.00004662333,0.996801,0.0000893109,0.000145474,0.002058197],"study_design_scores_gemma":[0.00004458728,0.0006922156,0.001448134,0.00000943942,0.000009937738,0.0001472446,0.00001853831,0.0005917588,0.9939622,0.00004003625,0.003032251,0.000003642085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864324,0.004117785,0.003755633,0.0003474651,0.0002506384,0.00006978161,0.0003648265,0.0001543835,0.004507232],"genre_scores_gemma":[0.9920036,0.00161328,0.0024436,0.0001718641,0.00002612887,0.00006062747,0.0005733292,0.00002904483,0.003078404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001997208,"threshold_uncertainty_score":0.006681323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02820513753339799,"score_gpt":0.2239386356619074,"score_spread":0.1957334981285095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}