{"id":"W1973720904","doi":"10.1139/o00-095","title":"Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell lines","year":2001,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; University of Pennsylvania","keywords":"Ornithine decarboxylase; Biology; Ornithine decarboxylase antizyme; Gene expression; Cell culture; Molecular biology; Regulation of gene expression; Cycloheximide; Cell growth; Adenosylmethionine decarboxylase; Protein biosynthesis; Gene; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009274019,0.0003040191,0.0001586627,0.0002320919,0.0000899589,0.0001772868,0.0000931137,0.0001634917,0.0008374003],"category_scores_gemma":[0.0001034826,0.0001216708,0.0002188163,0.0001561595,0.0001442881,0.0001167743,0.0001102861,0.0003115239,0.0002883721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001944062,"about_ca_system_score_gemma":0.000174922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001051298,"about_ca_topic_score_gemma":0.001251578,"domain_scores_codex":[0.9998716,0.00001953296,0.00001743834,0.00002652121,0.00003688822,0.00002813014],"domain_scores_gemma":[0.9998434,0.00002887617,0.00004429058,0.00003001467,0.00002199779,0.00003129965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002661858,0.000005150389,0.00009154907,0.000004956393,7.858818e-7,0.00002033232,0.000006880922,0.00001135946,0.9996997,0.00001256205,0.000002803066,0.0001174005],"study_design_scores_gemma":[0.000003046716,0.0001846102,0.005899079,0.000001676437,0.000004669086,0.0002010105,0.00002360056,0.0003349859,0.9927598,0.00001327364,0.0005713583,0.000002924613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969665,0.0005175324,0.001381177,0.00001975814,0.00001303944,0.00001601672,0.000363493,0.00005774127,0.0006647599],"genre_scores_gemma":[0.9945426,0.0004601788,0.001560593,0.00001665336,0.000004962445,0.00003258357,0.0008520258,0.00001798885,0.00251232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001051298,"threshold_uncertainty_score":0.002801359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006645428964059306,"score_gpt":0.2321771315518125,"score_spread":0.2255317025877532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}