{"id":"W1973720904","doi":"10.1139/o00-095","title":"Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell lines","year":2001,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; University of Pennsylvania","keywords":"Ornithine decarboxylase; Biology; Ornithine decarboxylase antizyme; Gene expression; Cell culture; Molecular biology; Regulation of gene expression; Cycloheximide; Cell growth; Adenosylmethionine decarboxylase; Protein biosynthesis; Gene; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001465039,0.0002075667,0.0002391562,0.00005406851,0.00005588544,0.00001023539,0.00009317851,0.0002770649,0.00001246152],"category_scores_gemma":[0.00005199202,0.0001815195,0.00003112004,0.0001102333,0.0002156481,0.000007098802,0.00009789949,0.0001073587,5.130242e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003519435,"about_ca_system_score_gemma":0.00004122279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002731255,"about_ca_topic_score_gemma":0.0000131927,"domain_scores_codex":[0.9988948,0.00005872986,0.0003248248,0.0004462102,0.00005271782,0.0002226984],"domain_scores_gemma":[0.9994457,0.00004039507,0.0001271558,0.0002138387,0.00004770928,0.0001252331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000172435,0.0001025354,0.00656129,0.0001080935,0.000005996441,0.000001382604,0.00004044407,0.000001117468,0.9918821,0.000006755027,0.00003995978,0.001077876],"study_design_scores_gemma":[0.001500103,0.0001328192,0.007956299,0.00002657517,0.00002044275,0.00002720112,0.00004953331,0.0001099572,0.9876713,0.0001075337,0.002203385,0.0001948431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930203,0.006052956,0.0001538726,0.0001275515,0.00002787153,0.0001997338,0.00007201372,0.000009916151,0.0003358083],"genre_scores_gemma":[0.9955763,0.002692817,0.0006787048,0.0000454583,0.0001276044,0.00003148673,0.0005662934,0.00001427925,0.0002671049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004210806,"threshold_uncertainty_score":0.7402148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006645428964059306,"score_gpt":0.2321771315518125,"score_spread":0.2255317025877532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}