{"id":"W1973722927","doi":"10.1074/jbc.m103999200","title":"Mitochondrial Respiratory Chain Deficiency inCaenorhabditis elegans Results in Developmental Arrest and Increased Life Span","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; University of Alberta","funders":"","keywords":"Biology; Caenorhabditis elegans; Mitochondrial biogenesis; Respiratory chain; ATP synthase; Gene; Genetics; Mitochondrial DNA; Mitochondrion; Mitochondrial respiratory chain; Cell biology; Protein subunit; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001091894,0.0005312703,0.0002094105,0.0002689881,0.0003124943,0.0002556174,0.000255292,0.0003931176,0.001033081],"category_scores_gemma":[0.0001291399,0.0002011733,0.0002275596,0.0001102911,0.0002150435,0.0001969289,0.0002276876,0.0006058721,0.0005026399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000594689,"about_ca_system_score_gemma":0.0003584286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00209247,"about_ca_topic_score_gemma":0.004428643,"domain_scores_codex":[0.9998561,0.00001049404,0.00002222414,0.00003527307,0.00004569831,0.00003031145],"domain_scores_gemma":[0.9997233,0.00003281636,0.00008316784,0.00002441763,0.00002889556,0.0001075141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008159137,0.00003212699,0.0003651315,0.00003574737,0.000003608366,0.000106004,0.000007384002,0.00003103692,0.9985513,0.00003304861,0.0000767332,0.0006764152],"study_design_scores_gemma":[0.00004886335,0.0005044322,0.03450925,0.0000412822,0.00003079899,0.00091615,0.00004476143,0.001444427,0.9580093,0.00008266568,0.004348267,0.0000197009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950227,0.001126922,0.0009356972,0.00009712231,0.00005510233,0.00003141457,0.001109841,0.0001839305,0.001437216],"genre_scores_gemma":[0.9910185,0.0007862935,0.001926558,0.00008983347,0.00001308268,0.00006805494,0.001428577,0.00004305056,0.004625909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00209247,"threshold_uncertainty_score":0.00431478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02259903819126027,"score_gpt":0.2324612298406927,"score_spread":0.2098621916494324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}