{"id":"W1973770560","doi":"10.3899/jrheum.090255","title":"Adaptation of Human CD4+ T Cells to Pathophysiological Hypoxia: A Transcriptome Analysis","year":2009,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bundesministerium für Bildung und Forschung","keywords":"Transcriptome; Hypoxia (environmental); Immune system; Inflammation; Biology; Cell biology; Synovial membrane; Immunology; Gene expression; Microarray analysis techniques; Medicine; Molecular biology; Gene; Chemistry; Biochemistry; Oxygen","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001088194,0.0001898636,0.0002385747,0.0002671349,0.0002446843,0.0002808007,0.0001118225,0.0002267399,0.001236619],"category_scores_gemma":[0.0001609795,0.0001007312,0.0002470149,0.0004586208,0.0001267095,0.0001292827,0.0001851221,0.0001998669,0.0004575928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001558685,"about_ca_system_score_gemma":0.0001458217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000463013,"about_ca_topic_score_gemma":0.0005609666,"domain_scores_codex":[0.9998512,0.00002173633,0.000008012386,0.00005795331,0.00002920611,0.00003189638],"domain_scores_gemma":[0.9999334,0.0000153733,0.00001651698,0.000006652881,0.00001813898,0.000009935922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002113117,0.00001553365,0.002548433,0.00007924181,0.00001225639,0.00003808981,0.0000472901,0.0001264277,0.9932367,0.00001629023,0.00008334063,0.00358493],"study_design_scores_gemma":[0.00007457244,0.001634933,0.4113146,0.00006223148,0.0002693823,0.00115249,0.0005698383,0.004675471,0.5689569,0.0002913689,0.0109708,0.00002755651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869825,0.002941419,0.005629967,0.0001141466,0.00002510822,0.00006156717,0.003030953,0.00005327763,0.001161187],"genre_scores_gemma":[0.9773244,0.002410537,0.009260139,0.000161085,0.00005634707,0.0002199634,0.008350939,0.00002492297,0.002191623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236619,"threshold_uncertainty_score":0.00413692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01279229466772574,"score_gpt":0.2553234810392233,"score_spread":0.2425311863714976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}