{"id":"W1973816835","doi":"10.1111/j.1582-4934.2012.01560.x","title":"Elastin overexpression by cell‐based gene therapy preserves matrix and prevents cardiac dilation","year":2012,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; National Institutes of Health; Canada Research Chairs","keywords":"Elastin; Extracellular matrix; Cardiac function curve; Stromal cell; Genetic enhancement; Myocardial infarction; Diastole; Cardiology; Heart failure; Medicine; Chemistry; Internal medicine; Cell biology; Pathology; Biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005245337,0.0001871851,0.000465918,0.0001419399,0.00004755211,0.000006328326,0.00004459884,0.00009583148,0.00003892785],"category_scores_gemma":[0.00007741708,0.0001162458,0.00007311803,0.00009250731,0.00009126823,0.00008138436,0.00001694522,0.0002449971,4.771683e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001959201,"about_ca_system_score_gemma":0.00002893069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005846512,"about_ca_topic_score_gemma":1.410634e-8,"domain_scores_codex":[0.9987509,0.0001037299,0.0003651341,0.0001227496,0.0004491646,0.0002083782],"domain_scores_gemma":[0.9991298,0.00005247214,0.0002006985,0.0001374256,0.00009149443,0.0003880773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001369182,0.0001087348,0.003362177,0.0001115965,0.00008753044,0.00002661769,0.0002873537,0.00002686091,0.9926029,0.00001643442,0.001872395,0.001360432],"study_design_scores_gemma":[0.004986933,0.001400552,0.006508056,0.0006653576,0.0003166042,0.0001099216,0.00008387714,0.0002455297,0.9458063,0.000009604424,0.03972417,0.0001430491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6942154,0.2697356,0.03485567,0.0006986083,0.0002657292,0.0001670479,0.000002402599,0.000008427279,0.00005112812],"genre_scores_gemma":[0.993679,0.002349937,0.001907969,0.00007414195,0.0007525486,0.000002897367,0.0000288075,0.0000288451,0.001175782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2994637,"threshold_uncertainty_score":0.4740365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009405087820884343,"score_gpt":0.2625550657107874,"score_spread":0.2531499778899031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}