{"id":"W1973826424","doi":"10.3109/00365540903496536","title":"Reduced HIV-1 long terminal repeat transcription in subjects with protective interferon regulatory factor-1 genotype: A potential mechanism mediating resistance to infection by HIV-1","year":2010,"lang":"en","type":"article","venue":"Scandinavian Journal of Infectious Diseases","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Biology; Long terminal repeat; Peripheral blood mononuclear cell; Interferon regulatory factors; Virology; Genotype; Haplotype; Transcription factor; Interferon; Immunology; Allele; Vesicular stomatitis virus; IRF1; Virus; Gene; Gene expression; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000215261,0.0003110337,0.0002899125,0.0004408785,0.0003585884,0.0003146128,0.0001549924,0.000467188,0.002364326],"category_scores_gemma":[0.0005301342,0.0001737571,0.0001519057,0.0002712948,0.0002285975,0.000154409,0.0001164677,0.0002734697,0.0002416672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009396258,"about_ca_system_score_gemma":0.00009670933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005902917,"about_ca_topic_score_gemma":0.0004468449,"domain_scores_codex":[0.9998506,0.00004190499,0.00001157749,0.00005106093,0.00001401517,0.00003075329],"domain_scores_gemma":[0.9998291,0.00004029285,0.00007127425,0.00001478922,0.00001304699,0.00003161488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002792228,0.0002262422,0.9130854,0.00007473579,0.00007079676,0.001561868,0.0006560241,0.00009061627,0.07330573,0.000170654,0.0001729702,0.007792734],"study_design_scores_gemma":[0.0000407506,0.0006608795,0.9919806,0.00001439593,0.00007148606,0.003621238,0.0002571223,0.0002573252,0.002592244,0.0001618398,0.0003334575,0.00000874106],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995158,0.0001695251,0.00009871193,0.00002345663,0.000003917354,0.000002979836,0.00003771001,0.000003796775,0.0001440665],"genre_scores_gemma":[0.9996767,0.00004251644,0.00008136199,0.00001453563,0.000008012447,0.000002819694,0.00003703724,0.000002478821,0.000134527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002364326,"threshold_uncertainty_score":0.007909477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005000333381235282,"score_gpt":0.2273159220486868,"score_spread":0.2223155886674515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}