{"id":"W1973826424","doi":"10.3109/00365540903496536","title":"Reduced HIV-1 long terminal repeat transcription in subjects with protective interferon regulatory factor-1 genotype: A potential mechanism mediating resistance to infection by HIV-1","year":2010,"lang":"en","type":"article","venue":"Scandinavian Journal of Infectious Diseases","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Biology; Long terminal repeat; Peripheral blood mononuclear cell; Interferon regulatory factors; Virology; Genotype; Haplotype; Transcription factor; Interferon; Immunology; Allele; Vesicular stomatitis virus; IRF1; Virus; Gene; Gene expression; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002372657,0.0002673223,0.0003842812,0.0004947071,0.0002473625,0.00005840036,0.0001441078,0.0001744064,0.0001851371],"category_scores_gemma":[0.0001630299,0.0002143319,0.0001438519,0.0002889536,0.0001420795,0.0003324384,0.00002565003,0.0007533503,0.00005847846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003785247,"about_ca_system_score_gemma":0.0002180619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001069192,"about_ca_topic_score_gemma":0.0009644135,"domain_scores_codex":[0.9982761,0.0003191689,0.0004494988,0.0003302188,0.0001641285,0.0004609502],"domain_scores_gemma":[0.9989865,0.00005156676,0.0003214455,0.000211511,0.0002382326,0.000190778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004644246,0.000646416,0.1770678,0.00007812048,0.0003015505,0.0003653328,0.001178972,0.00002239049,0.8108695,0.00002834369,0.0005126861,0.004284584],"study_design_scores_gemma":[0.008245759,0.004934043,0.742754,0.0007781108,0.0002330098,0.001610152,0.0002776806,0.000002289672,0.240064,0.000415017,0.0001641654,0.0005217415],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959357,0.0004136325,0.002004172,0.0001301528,0.0005594589,0.0006278408,0.0001949041,0.00004419309,0.00008995207],"genre_scores_gemma":[0.9992769,0.00003096148,0.00004496457,0.00001859244,0.0001111992,0.00007075805,0.00008352,0.0000304776,0.0003325965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5708055,"threshold_uncertainty_score":0.8740202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005000333381235282,"score_gpt":0.2273159220486868,"score_spread":0.2223155886674515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}