{"id":"W1973881933","doi":"10.1615/critrevtherdrugcarriersyst.2013007419","title":"A Pharmacokinetic Overview of Nanotechnology-Based Drug Delivery Systems: An ADME-Oriented Approach","year":2013,"lang":"en","type":"review","venue":"Critical Reviews in Therapeutic Drug Carrier Systems","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"ADME; Pharmacokinetics; Drug delivery; Drug; Pharmacology; Distribution (mathematics); Medicine; Nanotechnology; Materials science; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007226742,0.001152159,0.001514821,0.00282576,0.0003420242,0.0009405791,0.0007274,0.001342361,0.002045123],"category_scores_gemma":[0.0005614932,0.000538532,0.0007092506,0.002023697,0.0005748913,0.001669681,0.0006204412,0.002146201,0.001566104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009418156,"about_ca_system_score_gemma":0.001142406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008965122,"about_ca_topic_score_gemma":0.00121852,"domain_scores_codex":[0.9996295,0.00007270343,0.00005079837,0.00006298933,0.0001552212,0.00002877466],"domain_scores_gemma":[0.9997129,0.0001228461,0.00004256594,0.00000884192,0.00009672744,0.00001604922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001254731,0.000271548,0.0002841085,0.02617049,0.0001189321,0.0006979915,0.000156479,0.001946767,0.04351898,0.01743381,0.02084639,0.8884289],"study_design_scores_gemma":[0.00001840421,0.0005131822,0.0008829611,0.001893598,0.000126437,0.003478253,0.00006410017,0.001145118,0.01066497,0.004441006,0.9767066,0.00006534361],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003760866,0.992814,0.003782459,0.0004755631,0.0002651969,0.00003085424,0.00003396592,0.00002559246,0.002196316],"genre_scores_gemma":[0.002659465,0.9915184,0.003463649,0.0003607326,0.0003705893,0.00005121598,0.00005543057,0.000005502798,0.001515097],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00282576,"threshold_uncertainty_score":0.0068416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09040764381028385,"score_gpt":0.3655532596398149,"score_spread":0.275145615829531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}