{"id":"W1973901905","doi":"10.4161/onci.26013","title":"Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8<sup>+</sup>T-cell responses to anticancer vaccines","year":2013,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre; University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Vesicular stomatitis virus; Cytotoxic T cell; Adoptive cell transfer; CD8; Immunology; Biology; Priming (agriculture); Virology; Granzyme; Granzyme B; T cell; Vaccination; Viral vector; Immune system; Virus; Perforin; Recombinant DNA; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001366532,0.0004202105,0.0002346118,0.0001542754,0.00008587052,0.0003102213,0.0001795864,0.0002098413,0.001547048],"category_scores_gemma":[0.0001384607,0.0001404202,0.0001622971,0.00007625961,0.0002331003,0.000215169,0.0001373735,0.0006627972,0.0004699021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002761403,"about_ca_system_score_gemma":0.000225669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000366483,"about_ca_topic_score_gemma":0.0008740425,"domain_scores_codex":[0.9998723,0.00002423379,0.00001060574,0.00002086903,0.00003071626,0.00004113741],"domain_scores_gemma":[0.9999117,0.00002079261,0.00001867962,0.00001442491,0.00001474356,0.00001964042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001245056,0.00004022535,0.00005829436,0.00001812611,0.00000270208,0.000005610721,0.000004971312,0.00007326479,0.9978133,0.00005181407,0.00005007424,0.001756905],"study_design_scores_gemma":[0.00001784087,0.0002537715,0.0005861123,0.000002342468,0.00001037026,0.00003653399,0.000004162727,0.0002219135,0.9980702,0.00002305361,0.000772502,0.000001282018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911864,0.001169665,0.003973853,0.0001468844,0.00006949461,0.00003826505,0.0003262246,0.0003221858,0.002767053],"genre_scores_gemma":[0.9922699,0.0005737692,0.002299198,0.00007308016,0.00002080226,0.00003142845,0.0003288766,0.00007143943,0.004331441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001547048,"threshold_uncertainty_score":0.005175352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01790781444858435,"score_gpt":0.3123731776565138,"score_spread":0.2944653632079295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}