{"id":"W1973969059","doi":"10.1634/stemcells.2006-0209","title":"Cooperation of Matrix Metalloproteinases with the RhoA/Rho Kinase and Mitogen‐Activated Protein Kinase Kinase‐1/Extracellular Signal‐Regulated Kinase Signaling Pathways Is Required for the Sphingosine‐1‐Phosphate‐Induced Mobilization of Marrow‐Derived Stromal Cells","year":2006,"lang":"en","type":"article","venue":"Stem Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Université du Québec à Montréal","funders":"","keywords":"Cell biology; RHOA; Biology; Focal adhesion; Rho-associated protein kinase; Signal transduction; MAP kinase kinase kinase; ASK1; MAPK/ERK pathway; Protein kinase A; MAP2K7; Mitogen-activated protein kinase kinase; Sphingosine-1-phosphate; Cyclin-dependent kinase 9; Kinase; Sphingosine; Cyclin-dependent kinase 2; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005698989,0.0004293639,0.0004772478,0.00009068489,0.0003435074,0.00009563418,0.000278362,0.0002442894,0.0000589052],"category_scores_gemma":[0.00002315751,0.0002918427,0.0002468773,0.0003292166,0.0002173114,0.00003811254,0.00009719447,0.0001543122,0.000001579274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003624997,"about_ca_system_score_gemma":0.0001450772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004126922,"about_ca_topic_score_gemma":0.00005808753,"domain_scores_codex":[0.9977054,0.0002427464,0.0007340624,0.0006157178,0.0003253198,0.0003767397],"domain_scores_gemma":[0.9978485,0.0001123111,0.0007287816,0.000587556,0.0006407063,0.00008215129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001635873,0.0002198586,0.000003837328,0.0001984378,0.0002117681,0.000006162367,0.0001951647,0.001749571,0.9946393,0.0005270465,0.0001160259,0.000496941],"study_design_scores_gemma":[0.00308002,0.0009091389,0.000005282522,0.0001396807,0.0002842929,0.00000549628,0.0005063999,0.009988737,0.9837935,0.0000564492,0.0008891089,0.0003418905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.974788,0.003391559,0.01804429,0.0001509941,0.0001358688,0.003233297,0.0002168291,0.00002301597,0.0000161989],"genre_scores_gemma":[0.9976251,0.00006024028,0.0005464908,0.00002983727,0.0001090935,0.0003072503,0.0002897478,0.00007995762,0.0009523551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02283708,"threshold_uncertainty_score":0.9999534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213253338232765,"score_gpt":0.2147371278498377,"score_spread":0.2026045944675101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}