{"id":"W1973969059","doi":"10.1634/stemcells.2006-0209","title":"Cooperation of Matrix Metalloproteinases with the RhoA/Rho Kinase and Mitogen‐Activated Protein Kinase Kinase‐1/Extracellular Signal‐Regulated Kinase Signaling Pathways Is Required for the Sphingosine‐1‐Phosphate‐Induced Mobilization of Marrow‐Derived Stromal Cells","year":2006,"lang":"en","type":"article","venue":"Stem Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; Université du Québec à Montréal","funders":"","keywords":"Cell biology; RHOA; Biology; Focal adhesion; Rho-associated protein kinase; Signal transduction; MAP kinase kinase kinase; ASK1; MAPK/ERK pathway; Protein kinase A; MAP2K7; Mitogen-activated protein kinase kinase; Sphingosine-1-phosphate; Cyclin-dependent kinase 9; Kinase; Sphingosine; Cyclin-dependent kinase 2; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000214508,0.0005568137,0.0002941531,0.0002728204,0.0001963773,0.0003472745,0.0001519209,0.0002183505,0.001055476],"category_scores_gemma":[0.0001613249,0.0001885429,0.0003643571,0.0001270836,0.0002300448,0.0002169667,0.0003601824,0.0004933011,0.0005994818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002007569,"about_ca_system_score_gemma":0.0004760952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002744586,"about_ca_topic_score_gemma":0.0004120075,"domain_scores_codex":[0.9997533,0.00004587604,0.00002736109,0.00003602744,0.00008965584,0.00004773552],"domain_scores_gemma":[0.9998187,0.00002174356,0.00007532092,0.00002193296,0.00001851109,0.00004378615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006007515,0.00002437027,0.0002584528,0.00004776235,0.000004967609,0.0001236038,0.00001356259,0.00003594624,0.9968514,0.000169066,0.000051836,0.0023589],"study_design_scores_gemma":[0.00002015334,0.0002339161,0.008156961,0.000009369796,0.00001679767,0.0007813561,0.00003003604,0.001088048,0.9849689,0.0001456831,0.0045426,0.000006097613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757248,0.00839065,0.01184704,0.0003049891,0.00005224291,0.0001345923,0.0005199459,0.0002861369,0.00273968],"genre_scores_gemma":[0.9888873,0.00297575,0.005230965,0.00003868484,0.00003539154,0.0001223392,0.0006113378,0.00002425365,0.002073994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001055476,"threshold_uncertainty_score":0.00353092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01213253338232765,"score_gpt":0.2147371278498377,"score_spread":0.2026045944675101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}