{"id":"W1974034780","doi":"10.1002/ana.10519","title":"Interleukin‐1β promotes oligodendrocyte death through glutamate excitotoxicity","year":2003,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":255,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Excitotoxicity; NBQX; Glutamate receptor; Microglia; AMPA receptor; Oligodendrocyte; Kainate receptor; Neuroglia; Neuroscience; Biology; Immunology; Chemistry; Receptor; Inflammation; Biochemistry; Central nervous system; Myelin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001580078,0.0003057317,0.0001928532,0.0002040073,0.0001587751,0.0003099399,0.00008672223,0.0001768225,0.001368192],"category_scores_gemma":[0.0001644752,0.0001053098,0.000201578,0.0001169367,0.0001996846,0.0001689665,0.000226222,0.0004616531,0.0004072492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001569066,"about_ca_system_score_gemma":0.0001327852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002627544,"about_ca_topic_score_gemma":0.0003612755,"domain_scores_codex":[0.9998715,0.00003355671,0.00001119298,0.00001191135,0.00003373834,0.00003803326],"domain_scores_gemma":[0.9998716,0.00002762323,0.00002783823,0.00001533186,0.00002333577,0.00003414144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007302859,0.0001137021,0.001363417,0.0001591893,0.0000172029,0.0007008382,0.0001149161,0.00006977244,0.9909434,0.000287893,0.0002545509,0.005244874],"study_design_scores_gemma":[0.000489615,0.004788171,0.04418898,0.0001623937,0.0001358637,0.004833448,0.0003666836,0.001306854,0.9284728,0.001149669,0.01408822,0.00001718568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921086,0.004897689,0.0007347066,0.0001139247,0.00004565194,0.00001044634,0.00005054925,0.00003961792,0.001998701],"genre_scores_gemma":[0.9950079,0.003134082,0.000401355,0.00007056617,0.00003689053,0.00002019773,0.00008401641,0.000008139481,0.001236914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001368192,"threshold_uncertainty_score":0.004577041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1798106727191493,"score_gpt":0.3975565479564019,"score_spread":0.2177458752372526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}