{"id":"W1974034780","doi":"10.1002/ana.10519","title":"Interleukin‐1β promotes oligodendrocyte death through glutamate excitotoxicity","year":2003,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":255,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Excitotoxicity; NBQX; Glutamate receptor; Microglia; AMPA receptor; Oligodendrocyte; Kainate receptor; Neuroglia; Neuroscience; Biology; Immunology; Chemistry; Receptor; Inflammation; Biochemistry; Central nervous system; Myelin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003233599,0.0002102233,0.0005796388,0.0001215244,0.00007584058,0.000008554455,0.0001727898,0.0001335108,0.0001722146],"category_scores_gemma":[0.001426056,0.0001737013,0.0001681047,0.0001927798,0.0002925602,0.0001031296,0.0001300669,0.0003656278,0.00005869906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007368046,"about_ca_system_score_gemma":0.00006794216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008090091,"about_ca_topic_score_gemma":0.0000194938,"domain_scores_codex":[0.9980016,0.0002721825,0.000399966,0.0004076923,0.0003234851,0.0005950571],"domain_scores_gemma":[0.9987463,0.0002572184,0.000133696,0.0004501969,0.0002755855,0.0001369572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005941273,0.003924783,0.3040394,0.001770585,0.001998299,0.001545688,0.004685994,0.00006509432,0.6146184,0.02166106,0.03112143,0.008627979],"study_design_scores_gemma":[0.002022267,0.004113541,0.2792655,0.00008703285,0.00003731413,0.000329403,0.00004416243,0.0001413992,0.6739911,0.002596169,0.03711367,0.0002584148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836134,0.0005052043,0.00006981727,0.005127529,0.0001353728,0.0004520594,0.00001078771,0.00006501847,0.01002078],"genre_scores_gemma":[0.9938722,0.001553168,0.0003486997,0.00389042,0.00007887805,0.00004056598,0.000003694205,0.00002829588,0.0001840702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05937272,"threshold_uncertainty_score":0.7083335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1798106727191493,"score_gpt":0.3975565479564019,"score_spread":0.2177458752372526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}