{"id":"W1974070419","doi":"10.1529/biophysj.104.045310","title":"Direct Simulation of Transmembrane Helix Association: Role of Asparagines","year":2004,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Dimer; Hydrogen bond; Chemistry; Transmembrane domain; Trimer; Transmembrane protein; Coiled coil; Monomer; Peptide; Asparagine; Crystallography; Leucine zipper; Glycophorin; Protein structure; Helix (gastropod); Membrane; Stereochemistry; Molecule; Peptide sequence; Amino acid; Biochemistry; Organic chemistry; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007461313,0.00008497296,0.0001697418,0.00002681759,0.00003032783,0.000007428429,0.00009439704,0.00009391391,0.00001481762],"category_scores_gemma":[0.00003116918,0.00006891753,0.0001625716,0.0000763504,0.00003040366,0.000005863351,0.00001178793,0.00007517745,0.000001665263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001466699,"about_ca_system_score_gemma":0.0000557726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006940448,"about_ca_topic_score_gemma":0.000001642918,"domain_scores_codex":[0.9993413,0.00002563422,0.000222948,0.0001003901,0.000194319,0.0001154184],"domain_scores_gemma":[0.9995073,0.00001125959,0.0001813487,0.00009771468,0.0001504858,0.00005186532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006497808,0.0001016679,0.0004848959,0.00001175339,0.00004562657,8.485324e-7,0.00004314904,0.005504902,0.992668,0.00002764036,0.000007118127,0.001039471],"study_design_scores_gemma":[0.00065101,0.0002251765,0.00427674,0.00001499083,0.00005407418,0.000007944882,0.00001559108,0.00003066017,0.9936559,0.00004335442,0.000948321,0.00007622325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989865,0.00004569716,0.0003603748,0.0000739046,0.0001329461,0.00004843264,0.0000154198,0.000003406046,0.00033332],"genre_scores_gemma":[0.9990418,0.00003766761,0.0001632654,0.00002355341,0.0006473461,9.388038e-7,0.00001276389,0.000008474555,0.00006421319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005474242,"threshold_uncertainty_score":0.2810375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006285009015702436,"score_gpt":0.2469259777009725,"score_spread":0.24064096868527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}