{"id":"W1974070419","doi":"10.1529/biophysj.104.045310","title":"Direct Simulation of Transmembrane Helix Association: Role of Asparagines","year":2004,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Dimer; Hydrogen bond; Chemistry; Transmembrane domain; Trimer; Transmembrane protein; Coiled coil; Monomer; Peptide; Asparagine; Crystallography; Leucine zipper; Glycophorin; Protein structure; Helix (gastropod); Membrane; Stereochemistry; Molecule; Peptide sequence; Amino acid; Biochemistry; Organic chemistry; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002832556,0.0005847817,0.0006930834,0.0002353352,0.0009899631,0.0007959999,0.001361121,0.001097588,0.005751591],"category_scores_gemma":[0.001493797,0.0004486794,0.0003231104,0.0004138523,0.0007261781,0.0007970409,0.0005335685,0.001486269,0.000234122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001309017,"about_ca_system_score_gemma":0.001180587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009807979,"about_ca_topic_score_gemma":0.007358002,"domain_scores_codex":[0.9998381,0.00002736013,0.000004996692,0.00002609875,0.00003343229,0.00007004425],"domain_scores_gemma":[0.9991867,0.0004640385,0.00005160646,0.00007545493,0.00009858029,0.0001235954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00208794,0.0009071794,0.00521567,0.0002629441,0.0001735768,0.001000321,0.0004213469,0.9290723,0.03428124,0.01521849,0.002711585,0.008647349],"study_design_scores_gemma":[0.000249025,0.0002297237,0.0007291059,0.000009641569,0.00002485573,0.00003537505,0.0001180155,0.9872027,0.00906131,0.001677102,0.0006435577,0.00001954468],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919283,0.00007953799,0.002452482,0.0002502302,0.00005303437,0.00002174621,0.0001722057,0.00008985389,0.004952386],"genre_scores_gemma":[0.9981905,0.00006849654,0.0009979414,0.00004565369,0.000007191323,0.0000248809,0.0001267991,0.00002984268,0.0005088467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009807979,"threshold_uncertainty_score":0.01950175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006285009015702436,"score_gpt":0.2469259777009725,"score_spread":0.24064096868527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}