{"id":"W1974085861","doi":"10.1021/cb300221f","title":"Phosphorylation of the Synthetic Hexasaccharide Repeating Unit Is Essential for the Induction of Antibodies to <i>Clostridium difficile</i> PSII Cell Wall Polysaccharide","year":2012,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Clostridium difficile; Polysaccharide; Phosphorylation; Cell wall; Antibody; Chemistry; Clostridium; Microbiology; Cell; Biochemistry; Bacteria; Biology; Immunology; Antibiotics; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004598783,0.0002129947,0.0004344514,0.00008485607,0.0001295977,0.000007822344,0.0003369945,0.0002507154,0.0000921768],"category_scores_gemma":[0.0008932207,0.0001287047,0.0002433657,0.0004332037,0.0003115836,0.00004391096,0.0002504137,0.0003393151,0.00001041746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007126235,"about_ca_system_score_gemma":0.0001172608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002824471,"about_ca_topic_score_gemma":0.000002544676,"domain_scores_codex":[0.9982172,0.00005222427,0.0005965609,0.000319129,0.0002889931,0.0005258569],"domain_scores_gemma":[0.9980267,0.0006527392,0.0002714011,0.0006142536,0.0003058387,0.0001290493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003966489,0.0002529513,0.006260042,0.0001214818,0.00007508901,1.671476e-7,0.0004144181,0.000002907056,0.9891968,0.0001551345,0.0008206409,0.002303763],"study_design_scores_gemma":[0.0006597863,0.0001823198,0.0009374088,0.00006995555,0.0002037815,0.00001394701,0.0003064988,0.00007723679,0.9959096,0.00004676236,0.001466345,0.0001263929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937423,0.0008417459,0.00014196,0.003771052,0.0003531515,0.0008605214,0.00008475658,0.0000214114,0.0001830622],"genre_scores_gemma":[0.9986098,0.0001765342,0.0002109865,0.0003105919,0.0003855766,0.00005197459,0.00002901764,0.00002667941,0.0001988614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006712808,"threshold_uncertainty_score":0.5248424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02952165259044276,"score_gpt":0.3056635302543679,"score_spread":0.2761418776639252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}