{"id":"W1974127479","doi":"10.1016/j.resmic.2004.09.007","title":"A new family of mobilizable suicide plasmids based on broad host range R388 plasmid (IncW) and RP4 plasmid (IncPα) conjugative machineries and their cognate Escherichia coli host strains","year":2004,"lang":"en","type":"article","venue":"Research in Microbiology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":319,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Plasmid; Biology; Escherichia coli; Genetics; Bacterial conjugation; Gene; Transformation (genetics); Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006504859,0.0003526165,0.0005111145,0.000302787,0.0001344289,0.0000387308,0.0003565219,0.0007348986,0.00002653422],"category_scores_gemma":[0.0001802698,0.0002972886,0.0000666569,0.0003201186,0.001594162,0.000006906424,0.0004179342,0.0005564601,0.000006212251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005545288,"about_ca_system_score_gemma":0.0004400852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008223318,"about_ca_topic_score_gemma":0.00125043,"domain_scores_codex":[0.9976181,0.0003433506,0.0004111174,0.000773965,0.00009892713,0.0007545152],"domain_scores_gemma":[0.9990143,0.0001442622,0.0001188011,0.0003973545,0.0001542812,0.0001710319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001141188,0.0001527653,0.001548268,0.00006647165,0.00006261481,0.00001175767,0.000113772,0.0000926003,0.9957073,0.0002505308,0.0002396735,0.0006130544],"study_design_scores_gemma":[0.004323987,0.003664369,0.007205781,0.0001325006,0.000008484759,0.00002818853,0.0003230519,0.0001211498,0.9767584,0.0003461895,0.006742129,0.0003458169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955478,0.001521274,0.000130989,0.001058741,0.0001013894,0.0006691146,0.0006779444,0.00001625047,0.0002765156],"genre_scores_gemma":[0.9962134,0.001719599,0.001341876,0.0003133365,0.00006363182,0.00003916024,0.0001766353,0.00003889227,0.0000934851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01894895,"threshold_uncertainty_score":0.9999479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02432513610559084,"score_gpt":0.289124425086645,"score_spread":0.2647992889810541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}