{"id":"W1974132764","doi":"10.1371/journal.pone.0002327","title":"The Intermediate Filament Network in Cultured Human Keratinocytes Is Remarkably Extensible and Resilient","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Guelph","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Cancer Research UK","keywords":"Intermediate filament; Protein filament; Cytoskeleton; Biophysics; Actin; Treadmilling; Microtubule; In vitro; Tension (geology); Biology; Cell biology; Microfilament; Materials science; Cell; Biochemistry; Composite material; Compression (physics)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001019067,0.0001268056,0.00008806058,0.0002121091,0.0002056245,0.0002022648,0.00007365593,0.0001466853,0.0005206649],"category_scores_gemma":[0.0001792945,0.0001578331,0.000111743,0.0001401467,0.0001555217,0.0002637609,0.0001848554,0.0002139851,0.0001947487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067109,"about_ca_system_score_gemma":0.00008236652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000582202,"about_ca_topic_score_gemma":0.0006966654,"domain_scores_codex":[0.9999174,0.000009712102,0.000008685844,0.00002381296,0.00002960777,0.00001079221],"domain_scores_gemma":[0.999879,0.00001681905,0.00004030501,0.00002685643,0.00001583729,0.00002111917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003838222,0.000006085583,0.001288103,0.00002167181,0.000006575091,0.0001159522,0.00004799032,0.0001552936,0.9967326,0.00008965516,0.00001405381,0.001483748],"study_design_scores_gemma":[0.00001254163,0.0004887264,0.1176312,0.00003605026,0.00006569715,0.002520547,0.0003104043,0.00162424,0.8719345,0.0005757934,0.00477715,0.00002320436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940625,0.001212583,0.003012077,0.00004896332,0.000007197571,0.00001365651,0.000136288,0.00003376139,0.001472917],"genre_scores_gemma":[0.9965749,0.0006549461,0.001781338,0.00002769526,0.000003162638,0.00001410433,0.0002214906,0.000008374439,0.0007140323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000582202,"threshold_uncertainty_score":0.001741827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03352225972933207,"score_gpt":0.2560394203891774,"score_spread":0.2225171606598454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}