{"id":"W1974157104","doi":"10.1097/00007691-200106000-00015","title":"Quantitation of Free and Total Amphotericin B in Human Biologic Matrices by a Liquid Chromatography Tandem Mass Spectrometric Method","year":2001,"lang":"en","type":"article","venue":"Therapeutic Drug Monitoring","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Amphotericin B; Chromatography; Chemistry; Detection limit; Quantitative analysis (chemistry); Microbiology; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006200557,0.0001614842,0.0004104519,0.000420624,0.00006194782,0.00001606378,0.0001036286,0.00008236725,0.00002126947],"category_scores_gemma":[0.00004210207,0.0001361582,0.00008181632,0.001087188,0.00007824567,0.00009774323,0.00002752983,0.000162677,0.000001168022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006681137,"about_ca_system_score_gemma":0.0000189231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002775781,"about_ca_topic_score_gemma":0.00001128879,"domain_scores_codex":[0.9987277,0.0001167681,0.000367869,0.000289469,0.0002339967,0.0002641834],"domain_scores_gemma":[0.9993026,0.0001806044,0.0001337729,0.0002713212,0.00004825919,0.0000633977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001723578,0.00008284787,0.4816836,0.00006019037,0.00003649317,0.000007855003,0.0002590862,0.00000128744,0.5157405,0.00004872513,0.000004065726,0.001903043],"study_design_scores_gemma":[0.001399669,0.0007432306,0.8818233,0.0001804745,0.00008390845,0.00001672808,0.001622385,0.00007734854,0.1130232,0.0008038087,0.00004225825,0.0001836812],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881927,0.009253535,0.001717786,0.00008318133,0.00009077531,0.0002463867,0.000003680737,0.00004677026,0.0003651511],"genre_scores_gemma":[0.9956636,0.001420837,0.002709104,0.00001617666,0.00007583482,0.000009593921,0.000004450246,0.00001574628,0.00008465349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4027172,"threshold_uncertainty_score":0.5552371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02728749814547204,"score_gpt":0.3315307579202386,"score_spread":0.3042432597747665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}