{"id":"W1974163527","doi":"10.1074/jbc.m002518200","title":"Role of the Intracellular Domain of the Human Type I Interferon Receptor 2 Chain (IFNAR2c) in Interferon Signaling","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Institutes of Health; National Cancer Institute; National Institute of General Medical Sciences; Medical Research Council; U.S. Public Health Service; Medical Research Council Canada","keywords":"Interferon; Intracellular; Cell biology; Signal transduction; Receptor; Interferon type I; Domain (mathematical analysis); Chemistry; Biology; Virology; Genetics; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001831054,0.000372036,0.0002632499,0.0001386569,0.0002712547,0.0005596968,0.0001648899,0.0004975823,0.0007289571],"category_scores_gemma":[0.0001235505,0.0001341599,0.000287532,0.0001051089,0.0001965382,0.0002126291,0.0002474782,0.0004333435,0.0005064421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003830085,"about_ca_system_score_gemma":0.0002272433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006192264,"about_ca_topic_score_gemma":0.0006103014,"domain_scores_codex":[0.9998294,0.00004825857,0.00001662046,0.00003024781,0.00003611839,0.00003936947],"domain_scores_gemma":[0.9999087,0.00001400979,0.00002358892,0.00001698826,0.00001191228,0.00002480661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001394952,0.00001290069,0.0005668575,0.00001705349,0.000003827952,0.00009556665,0.000009875586,0.00009979174,0.998187,0.0001650689,0.00003141638,0.0006711775],"study_design_scores_gemma":[0.00005424296,0.0002560779,0.01646429,0.00002309491,0.00002908751,0.001451166,0.0000871907,0.004073013,0.9725993,0.0001690135,0.00477894,0.00001450159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913692,0.00349938,0.002440063,0.000171887,0.00003041162,0.000020674,0.0004284763,0.00003363975,0.002006204],"genre_scores_gemma":[0.9968832,0.0005659926,0.001304034,0.00005675184,0.000007197312,0.00001163247,0.0004707683,0.000006568262,0.0006937237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007289571,"threshold_uncertainty_score":0.002778888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02057724965793427,"score_gpt":0.2573142419090894,"score_spread":0.2367369922511551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}