{"id":"W1974168359","doi":"10.1038/cddis.2013.296","title":"Knockdown of specific host factors protects against influenza virus-induced cell death","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Children's Hospital Research Institute of Manitoba; Public Health Agency of Canada; University of Manitoba; Research Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Manitoba Health Research Council; Canadian Institutes of Health Research; University of Ottawa; Health Sciences Centre Foundation","keywords":"Gene knockdown; Gene silencing; Biology; Programmed cell death; Viral replication; RNA interference; Virus; Virology; Influenza A virus; Gene; Cell biology; Apoptosis; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006662442,0.0002922683,0.0003179324,0.0001454987,0.0001705465,0.00003746331,0.0002035779,0.0001853956,0.0008983823],"category_scores_gemma":[0.00006144653,0.0002325149,0.0001424953,0.00007841379,0.0001172294,0.0001442895,0.0001122986,0.0002324707,0.0004866775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000247931,"about_ca_system_score_gemma":0.0001338423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001484212,"about_ca_topic_score_gemma":0.000001430481,"domain_scores_codex":[0.9986776,0.0001639498,0.0003307873,0.0003489892,0.0000461294,0.0004325901],"domain_scores_gemma":[0.9990803,0.00009375191,0.0001347013,0.0003979201,0.00009151598,0.0002018154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000581699,0.0003201152,0.008889913,0.00009845534,0.00002968611,0.000007964545,0.000265755,6.103052e-7,0.9874792,0.0000877202,0.001706392,0.000532519],"study_design_scores_gemma":[0.001561786,0.0002988407,0.09705007,0.00004642009,0.00003357636,0.000001747666,0.0003221431,0.000003726693,0.8836984,0.0000437993,0.01662982,0.0003096767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862,0.007431688,0.00001326384,0.00002274389,0.0002576812,0.000632177,0.0000785092,0.00005530457,0.005308602],"genre_scores_gemma":[0.9963881,0.0002599797,0.00001777486,0.0002864504,0.00002001155,0.00004940366,0.00006390094,0.00002582136,0.002888499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1037808,"threshold_uncertainty_score":0.9836656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02132740291401366,"score_gpt":0.2313736930312303,"score_spread":0.2100462901172166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}