{"id":"W1974168359","doi":"10.1038/cddis.2013.296","title":"Knockdown of specific host factors protects against influenza virus-induced cell death","year":2013,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Children's Hospital Research Institute of Manitoba; Public Health Agency of Canada; University of Manitoba; Research Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Manitoba Health Research Council; Canadian Institutes of Health Research; University of Ottawa; Health Sciences Centre Foundation","keywords":"Gene knockdown; Gene silencing; Biology; Programmed cell death; Viral replication; RNA interference; Virus; Virology; Influenza A virus; Gene; Cell biology; Apoptosis; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001845613,0.0003880955,0.0004397889,0.0002134182,0.00014618,0.000297248,0.0001831054,0.0002229074,0.0008414412],"category_scores_gemma":[0.0001064787,0.000148422,0.0003212677,0.0001807713,0.0002193,0.0001408342,0.0001433088,0.0004373703,0.0003187633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002553414,"about_ca_system_score_gemma":0.0002461998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004334685,"about_ca_topic_score_gemma":0.001028065,"domain_scores_codex":[0.9998034,0.00002410574,0.00003334443,0.00004762228,0.0000534442,0.00003812868],"domain_scores_gemma":[0.9998903,0.00002809453,0.00002872491,0.00001722224,0.00001462289,0.00002092712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004537832,0.00002012702,0.00007592419,0.00003056876,0.000005416133,0.0000165508,0.000009038297,0.00003723333,0.9988247,0.00003623732,0.0000243787,0.0008745636],"study_design_scores_gemma":[0.00001397635,0.0003938072,0.002140089,0.000004377752,0.00002611884,0.00008854741,0.00001619202,0.0005833558,0.9947902,0.00001553639,0.001924494,0.000003379904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896381,0.002085287,0.005581928,0.0000773588,0.00004184628,0.0000907509,0.0007489756,0.0002206731,0.001514968],"genre_scores_gemma":[0.9884412,0.001873451,0.005115733,0.0000633668,0.00001247081,0.0001354499,0.001302817,0.00005883688,0.002996679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008414412,"threshold_uncertainty_score":0.002814889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02132740291401366,"score_gpt":0.2313736930312303,"score_spread":0.2100462901172166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}