{"id":"W1974263628","doi":"10.1074/jbc.m312621200","title":"Nm23-H2 Interacts with a G Protein-coupled Receptor to Regulate Its Endocytosis through an Rac1-dependent Mechanism","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Mechanisms of cancer metastasis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Fleurimont; Université de Sherbrooke","funders":"","keywords":"RAC1; Mechanism (biology); Endocytosis; Cell biology; Receptor-mediated endocytosis; Chemistry; Receptor; Biology; Signal transduction; Physics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108129,0.0003518444,0.0002877454,0.0001872305,0.000356707,0.0003708247,0.0002399551,0.0003906268,0.001916493],"category_scores_gemma":[0.0001113867,0.0001253632,0.0005138808,0.0001808326,0.0001461233,0.0002231592,0.0002742535,0.0003933833,0.0009670242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005296812,"about_ca_system_score_gemma":0.0001830834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009672836,"about_ca_topic_score_gemma":0.001208151,"domain_scores_codex":[0.9997993,0.00003626292,0.00001011962,0.00004008263,0.00005620557,0.00005798657],"domain_scores_gemma":[0.999954,0.00000570549,0.000008489827,0.000006136715,0.000008297101,0.00001732926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009596967,0.00002878936,0.0002500739,0.00004224621,0.00001469008,0.0002400449,0.00001560076,0.00005662956,0.9979849,0.0001351062,0.0001542827,0.0009816291],"study_design_scores_gemma":[0.00003442935,0.0002021699,0.01291445,0.00001066828,0.00003511038,0.001604796,0.0000830968,0.002569792,0.9691396,0.00008977394,0.01329279,0.00002324418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857991,0.005801116,0.003296925,0.0003399338,0.00008176964,0.00005072048,0.0005582018,0.000107346,0.003964921],"genre_scores_gemma":[0.9900172,0.002142114,0.00242464,0.0002100256,0.00003286534,0.0000631125,0.0009025106,0.00002817848,0.004179342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001916493,"threshold_uncertainty_score":0.006411314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02359904492748781,"score_gpt":0.2707182868444259,"score_spread":0.2471192419169381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}