{"id":"W1974300982","doi":"10.1016/j.freeradbiomed.2010.10.632","title":"Molecular Cytotoxic Mechanisms of Estradiol involve Estradiol Quinoid Moieties","year":2010,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cytotoxic T cell; Chemistry; Estrogen; Biology; Biochemistry; Endocrinology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003021919,0.0003244897,0.0001232785,0.0001426684,0.0002757346,0.0002430034,0.0003839588,0.0003792164,0.00394901],"category_scores_gemma":[0.0002399102,0.0001271305,0.000183326,0.00008049894,0.0004164411,0.0005111142,0.0002497408,0.0003842031,0.0004651443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002699503,"about_ca_system_score_gemma":0.0001789404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00017908,"about_ca_topic_score_gemma":0.0002274091,"domain_scores_codex":[0.9999286,0.00001655819,0.000002320271,0.00001412967,0.00001727447,0.00002112896],"domain_scores_gemma":[0.9998462,0.00006270764,0.00002573505,0.0000240252,0.00002673305,0.00001456999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006027866,0.0001041857,0.001243602,0.0002639228,0.00002598036,0.0007733292,0.0003394462,0.0004239983,0.957964,0.02274446,0.0004417213,0.01507265],"study_design_scores_gemma":[0.00002830838,0.0004502876,0.001324706,0.00001325146,0.00002088241,0.0005481191,0.0001058936,0.0005090645,0.987248,0.002930503,0.006809812,0.00001121289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9323077,0.01179578,0.03327144,0.001691084,0.0002305117,0.0001530629,0.0001873287,0.0001345163,0.02022867],"genre_scores_gemma":[0.9871321,0.0031011,0.001866472,0.0001735311,0.00002671711,0.00002801128,0.00007595879,0.000006547528,0.007589618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00394901,"threshold_uncertainty_score":0.01321077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004821887979105476,"score_gpt":0.2456313738885811,"score_spread":0.2408094859094756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}