{"id":"W1974409640","doi":"10.1016/j.it.2012.02.009","title":"CD73: a potent suppressor of antitumor immune responses","year":2012,"lang":"en","type":"review","venue":"Trends in Immunology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":365,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Health and Medical Research Council; National Medical Research Council; Medical Research Council; Victorian Cancer Agency","keywords":"Immunosurveillance; Adenosine; Immune system; Cancer research; Immunology; Tumor microenvironment; 5'-nucleotidase; Myeloid-derived Suppressor Cell; Carcinogenesis; Biology; Suppressor; Nucleotidase; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002847859,0.0003834247,0.001299544,0.0004913957,0.00003100423,0.000005931177,0.0005034495,0.0006315882,0.0002117114],"category_scores_gemma":[0.00006525491,0.0003287445,0.0004559204,0.0003114652,0.0001887994,0.000003335247,0.0003370356,0.0003282342,0.00002179573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002345087,"about_ca_system_score_gemma":0.0001236131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006109882,"about_ca_topic_score_gemma":0.000003816879,"domain_scores_codex":[0.9978842,0.0003853879,0.0008020512,0.0003904119,0.00008867672,0.0004493167],"domain_scores_gemma":[0.9987074,0.00006113886,0.0004274486,0.0007285691,0.00004011812,0.00003529486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003321038,0.0003597833,0.00005465773,0.001884395,0.0008090628,0.00005253455,0.00006378639,0.000002586884,0.01248308,0.0002597072,0.001644846,0.9820535],"study_design_scores_gemma":[0.0004303566,0.0002522729,0.0001566239,0.0008342962,0.0002969248,0.0002323672,0.00001340088,2.274806e-7,0.003575489,0.000006206476,0.993866,0.0003358907],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001827403,0.9966208,0.00001355437,0.00001756549,0.0003903759,0.0001256906,0.00007463211,0.00001011877,0.0009198831],"genre_scores_gemma":[0.009384843,0.986248,0.0001687766,0.000009965665,0.0002142001,0.00006132606,0.0006320468,0.00005630689,0.003224516],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9922211,"threshold_uncertainty_score":0.9999164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05217649283058647,"score_gpt":0.3429936773554892,"score_spread":0.2908171845249027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}