{"id":"W1974418327","doi":"10.1097/brs.0b013e3181cec247","title":"Region-Dependent Aggrecan Degradation Patterns in the Rat Intervertebral Disc Are Affected by Mechanical Loading In Vivo","year":2010,"lang":"en","type":"article","venue":"Spine","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Medicine; Aggrecan; Intervertebral disc; In vivo; Degradation (telecommunications); Anatomy; Biomedical engineering; Pathology; Osteoarthritis; Articular cartilage; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002802397,0.0001814283,0.0003179466,0.0001667582,0.00002969391,0.00002195908,0.0002169525,0.0001571367,0.0004798231],"category_scores_gemma":[0.0002439256,0.0001211063,0.0001035422,0.0002413972,0.00004047052,0.0001330619,0.00006908237,0.0006513608,0.00002311311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006185134,"about_ca_system_score_gemma":0.000023443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005415368,"about_ca_topic_score_gemma":0.009060701,"domain_scores_codex":[0.9986968,0.000120633,0.0003588495,0.0003247398,0.0001946342,0.0003043606],"domain_scores_gemma":[0.9994206,0.000008392418,0.000109175,0.0003571376,0.00003172319,0.00007291404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008589104,0.001258543,0.1188982,0.0001466012,0.00003780362,0.001098418,0.0007641347,6.824022e-7,0.8443772,0.001382954,0.02091451,0.01103512],"study_design_scores_gemma":[0.005474167,0.001353309,0.8798856,0.0008992212,0.00006523253,0.0006941949,0.001273317,0.001702846,0.1074233,0.000269828,0.0005578196,0.0004011585],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992566,0.000071144,0.001024044,0.004970936,0.0004797362,0.0004188186,0.00001011735,0.00003748809,0.000421695],"genre_scores_gemma":[0.9973347,0.00002433566,0.0001056584,0.001639704,0.0001351226,0.00005900331,0.00007864865,0.00002098083,0.0006017984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7609875,"threshold_uncertainty_score":0.5253726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01756849146945104,"score_gpt":0.2803283567541773,"score_spread":0.2627598652847263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}