{"id":"W1974423225","doi":"10.1006/bbrc.2002.6715","title":"The Short MCK1350 Promoter/Enhancer Allows for Sufficient Dystrophin Expression in Skeletal Muscles of mdx Mice","year":2002,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Biotechnology Research Institute; Montreal Neurological Institute and Hospital; McGill University","funders":"Duchenne Parent Project; Fonds pour la Formation de Chercheurs et l'Aide à la Recherche; Deutsche Forschungsgemeinschaft; Fonds de Recherche du Québec - Santé; Muscular Dystrophy Association","keywords":"Dystrophin; Duchenne muscular dystrophy; Utrophin; Enhancer; Minigene; ITGA7; Skeletal muscle; Muscular dystrophy; Biology; mdx mouse; Promoter; Molecular biology; Gene expression; Cell biology; Gene; Messenger RNA; Endocrinology; Genetics; Alternative splicing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004194607,0.0007977928,0.0005604855,0.0009278791,0.000371031,0.0005529544,0.0005566743,0.0007657373,0.003972117],"category_scores_gemma":[0.0003640309,0.0007281101,0.0005177082,0.0002746219,0.000868282,0.00052183,0.0007406549,0.001703649,0.001441938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006293188,"about_ca_system_score_gemma":0.0005537764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001225465,"about_ca_topic_score_gemma":0.003008586,"domain_scores_codex":[0.9995383,0.00003842224,0.00008347297,0.0001309858,0.0001049321,0.0001038588],"domain_scores_gemma":[0.9992247,0.000139091,0.0002200573,0.00007929689,0.00005384698,0.0002830808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006442549,0.0000143562,0.00009735754,0.00001591543,0.000003033724,0.00002952366,0.00001153029,0.00002681457,0.9990948,0.0001688775,0.00003151824,0.000441809],"study_design_scores_gemma":[0.00006484428,0.0001062513,0.005379285,0.00002214209,0.00002913663,0.0004724048,0.00003008671,0.0007429951,0.9885406,0.0001234547,0.004476464,0.00001242487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977265,0.0007988767,0.01603247,0.0003170731,0.0001197845,0.00007407787,0.002854305,0.0006362899,0.001902087],"genre_scores_gemma":[0.9589645,0.0006511344,0.01795574,0.0002947458,0.00007151458,0.0002047543,0.005662851,0.00105441,0.01514033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003972117,"threshold_uncertainty_score":0.01328802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06427662554411277,"score_gpt":0.3603292881392463,"score_spread":0.2960526625951335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}