{"id":"W1974465538","doi":"10.1021/bc034130j","title":"Efficient and Expedient Two-Step Pyranose-Retaining Fluorescein Conjugation of Complex Reducing Oligosaccharides:  Galectin Oligosaccharide Specificity Studies in a Fluorescence Polarization Assay","year":2003,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chemistry; Galectin; Pyranose; Fluorescence anisotropy; Fluorescence; Oligosaccharide; Conjugate; Acylation; Fluorescein; Fluorescent labelling; Biochemistry; Chromatography; Combinatorial chemistry; Biophysics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007866841,0.0003245465,0.0005653141,0.0001186684,0.000189467,0.00001731623,0.0001746639,0.0002740275,0.00020534],"category_scores_gemma":[0.0005507421,0.0003168367,0.00007722817,0.0003241618,0.0006524374,0.00004187931,0.00009326754,0.0003433028,0.00001021736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001661088,"about_ca_system_score_gemma":0.0001121696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003219391,"about_ca_topic_score_gemma":0.00003237533,"domain_scores_codex":[0.9977635,0.0002574615,0.0007333479,0.0006605031,0.00007775317,0.0005074173],"domain_scores_gemma":[0.9988753,0.0001919857,0.0003778376,0.0003174571,0.0001902584,0.00004721729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001267811,0.0001173601,0.00984168,0.0001905403,0.00008966027,0.000005788677,0.001330557,0.0001250944,0.9865934,0.0004210813,0.0001132151,0.001044855],"study_design_scores_gemma":[0.001809877,0.00008612638,0.002573317,0.0002497706,0.00003650744,0.00009056017,0.003143429,0.0003014235,0.9908316,0.00007612528,0.0004762745,0.0003250014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937412,0.004283459,0.0001624065,0.00005343769,0.0003461842,0.00035243,0.00003785697,0.00005017506,0.0009728104],"genre_scores_gemma":[0.998902,0.0002379602,0.0004472641,0.00003546805,0.00004174436,0.00004800372,0.00007463185,0.00002149641,0.0001914894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007268363,"threshold_uncertainty_score":0.9999284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03914638673926064,"score_gpt":0.2935927127742994,"score_spread":0.2544463260350388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}