{"id":"W1974469317","doi":"10.1089/adt.2009.0206","title":"Validation of a Rb <sup>+</sup> Uptake Assay for the Mouse Embryonic Stem Cell-Derived Cardiomyocytes Na <sup>+</sup> , K <sup>+</sup> ATPase","year":2010,"lang":"en","type":"article","venue":"Assay and Drug Development Technologies","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aurora College; BC Research (Canada)","funders":"","keywords":"Ouabain; Digitoxin; Embryonic stem cell; ATPase; Transporter; Ion transporter; Flux (metallurgy); Chemistry; Stem cell; Enzyme; Molecular biology; Cell biology; Biochemistry; Biology; Digoxin; Membrane; Sodium; Heart failure; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001842872,0.0008941367,0.0007217313,0.0005410036,0.0003613392,0.0005214703,0.0006491418,0.00081962,0.0008622975],"category_scores_gemma":[0.001341217,0.0003492248,0.0004526298,0.0003441233,0.0004401908,0.0003193948,0.0003495799,0.0007966449,0.001272729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003691878,"about_ca_system_score_gemma":0.0005300546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001541898,"about_ca_topic_score_gemma":0.002666565,"domain_scores_codex":[0.9982773,0.0005155726,0.0002356424,0.0002896942,0.0005767645,0.0001050336],"domain_scores_gemma":[0.9988604,0.0003215507,0.0001403783,0.0001866081,0.0003777375,0.0001134048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003257594,0.00001700617,0.0001461251,0.00001909955,0.000003575886,0.0000126954,0.00001679998,0.00004629754,0.999129,0.00002619875,0.00001334831,0.0005372352],"study_design_scores_gemma":[0.000005250293,0.0002540448,0.001530598,0.000003589106,0.00002056353,0.00008441723,0.00001242714,0.0006151893,0.9967513,0.000008790415,0.0007083825,0.000005503582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.8247048,0.002115832,0.1656254,0.0002627916,0.0001325919,0.0008733994,0.002047694,0.0009895342,0.003247963],"genre_scores_gemma":[0.8041841,0.002781776,0.1788993,0.0001599523,0.00005559104,0.001239323,0.004720012,0.0003430728,0.007616933],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001842872,"threshold_uncertainty_score":0.009746134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009486027515466072,"score_gpt":0.2114686776342374,"score_spread":0.2019826501187713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}