{"id":"W1974469317","doi":"10.1089/adt.2009.0206","title":"Validation of a Rb <sup>+</sup> Uptake Assay for the Mouse Embryonic Stem Cell-Derived Cardiomyocytes Na <sup>+</sup> , K <sup>+</sup> ATPase","year":2010,"lang":"en","type":"article","venue":"Assay and Drug Development Technologies","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aurora College; BC Research (Canada)","funders":"","keywords":"Ouabain; Digitoxin; Embryonic stem cell; ATPase; Transporter; Ion transporter; Flux (metallurgy); Chemistry; Stem cell; Enzyme; Molecular biology; Cell biology; Biochemistry; Biology; Digoxin; Membrane; Sodium; Heart failure; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001185564,0.0005432301,0.0005019412,0.0002183694,0.0005193548,0.00009294983,0.0006287848,0.0007269784,0.00001516045],"category_scores_gemma":[0.0001697607,0.0004258382,0.000243292,0.000298851,0.0003965335,0.00004599091,0.0002379717,0.0003842666,0.000009428478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000444353,"about_ca_system_score_gemma":0.0002679907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002001276,"about_ca_topic_score_gemma":0.00001710161,"domain_scores_codex":[0.9973921,0.00009003529,0.0006955853,0.0008027848,0.0004017158,0.0006177909],"domain_scores_gemma":[0.9983005,0.0001723138,0.0003026263,0.0007991928,0.0003412356,0.00008412581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009210095,0.0006414793,0.01248704,0.0009929679,0.001502004,0.00001979076,0.008066273,0.03511122,0.7221584,0.00127059,0.009708425,0.2071208],"study_design_scores_gemma":[0.001334348,0.0001208567,0.0005800817,0.00004265826,0.0001230168,0.0000122479,0.008332835,0.005761468,0.9351915,0.0001745887,0.04773983,0.0005865864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987541,0.001200056,0.008556042,0.00102384,0.0001099521,0.001025689,0.00008647774,0.0003154088,0.0001415679],"genre_scores_gemma":[0.9919894,0.0006410734,0.004231939,0.00006947901,0.0001054453,0.0003948195,0.0006687933,0.00006481413,0.001834209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2130331,"threshold_uncertainty_score":0.9998193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009486027515466072,"score_gpt":0.2114686776342374,"score_spread":0.2019826501187713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}