{"id":"W1974472589","doi":"10.1080/14660820310012727","title":"In vitro reactive nitrating species toxicity in dissociated spinal motor neurons from NFL (−/−) and<i>h</i>NFL (+/+) transgenic mice","year":2003,"lang":"en","type":"article","venue":"Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders","topic":"Spinal Cord Injury Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"ALS Society of Canada","keywords":"Sodium nitroprusside; Apoptosis; Neurofilament; Motor neuron; Peroxynitrite; Necrosis; Nitric oxide; Genetically modified mouse; Programmed cell death; Chemistry; Spinal cord; Biology; Internal medicine; Molecular biology; Pharmacology; Cell biology; Endocrinology; Transgene; Biochemistry; Neuroscience; Medicine; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003446287,0.0005420904,0.0003084533,0.000286736,0.0002151091,0.0003064125,0.0004040402,0.0003813136,0.001077727],"category_scores_gemma":[0.000155561,0.0002894637,0.0004681538,0.0001619596,0.0002235058,0.0002435199,0.0002553032,0.0007029139,0.0007869239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004140397,"about_ca_system_score_gemma":0.0002347995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002504297,"about_ca_topic_score_gemma":0.005174882,"domain_scores_codex":[0.9997017,0.00002727616,0.00005109283,0.00008347881,0.00008089107,0.00005554241],"domain_scores_gemma":[0.9998118,0.00002794309,0.00006114372,0.00002808118,0.0000283247,0.00004270825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005419833,0.00002240832,0.0001168406,0.00002321774,0.000004901997,0.00004670557,0.00002272082,0.00004300504,0.9993178,0.00002568928,0.00001842153,0.0003042283],"study_design_scores_gemma":[0.00001869283,0.0005590371,0.004474206,0.00001449039,0.00003066508,0.0003290691,0.00004591098,0.0006853416,0.9923812,0.00004361347,0.001411946,0.000005810577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890492,0.002042305,0.004719963,0.00008913456,0.00008445878,0.00007705521,0.001400425,0.0001110501,0.002426457],"genre_scores_gemma":[0.9776659,0.002426533,0.007544164,0.0001191009,0.00003275785,0.0001800704,0.003488896,0.00008853489,0.008454124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002504297,"threshold_uncertainty_score":0.004979432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03443223972333984,"score_gpt":0.2812132025187836,"score_spread":0.2467809627954437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}