{"id":"W1974546936","doi":"10.1002/ibd.21177","title":"Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate†","year":2009,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":329,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Butyrate; Barrier function; Internalization; Biology; Intestinal epithelium; Cell biology; Oxidative stress; Chromosomal translocation; Epithelium; Short-chain fatty acid; Transcytosis; Intestinal mucosa; Microbiology; Biochemistry; Chemistry; Internal medicine; Cell; Endocytosis; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001923373,0.0002896302,0.0004891129,0.000096584,0.0001481222,0.0004283722,0.0001546925,0.0003740198,0.002034004],"category_scores_gemma":[0.0002586039,0.000165232,0.0003405048,0.0001147463,0.0002163199,0.0003055172,0.000303102,0.0006217011,0.0005424915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001911502,"about_ca_system_score_gemma":0.0001192107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002933879,"about_ca_topic_score_gemma":0.0003878617,"domain_scores_codex":[0.9997981,0.00005252321,0.0000253743,0.00003243851,0.000041373,0.00005017155],"domain_scores_gemma":[0.9997239,0.00004328059,0.00009531654,0.0000306582,0.00003987263,0.00006694509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005847721,0.00001631392,0.0007225108,0.00004752069,0.00000586596,0.00006139326,0.00001143808,0.000009926966,0.9980168,0.000006214424,0.00001166672,0.0005056345],"study_design_scores_gemma":[0.00004560939,0.001853173,0.05366683,0.00002255751,0.00004682387,0.0009474197,0.0001862513,0.0004123122,0.9408868,0.00005160267,0.001873673,0.000006901312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951617,0.003065334,0.000971459,0.0002389537,0.00003475319,0.00001614879,0.0001455906,0.00002625218,0.0003398228],"genre_scores_gemma":[0.9971228,0.0009921233,0.0008521513,0.0001037835,0.00001384827,0.00001729194,0.0002332093,0.0000157221,0.0006490186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002034004,"threshold_uncertainty_score":0.006804407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005804796394919567,"score_gpt":0.2638674332056821,"score_spread":0.2580626368107626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}