{"id":"W1974546936","doi":"10.1002/ibd.21177","title":"Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate†","year":2009,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":329,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Butyrate; Barrier function; Internalization; Biology; Intestinal epithelium; Cell biology; Oxidative stress; Chromosomal translocation; Epithelium; Short-chain fatty acid; Transcytosis; Intestinal mucosa; Microbiology; Biochemistry; Chemistry; Internal medicine; Cell; Endocytosis; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007727445,0.0001964151,0.000215942,0.00002395602,0.000084747,0.00002522605,0.0002124697,0.0001493894,0.00007300737],"category_scores_gemma":[0.00003006043,0.000191804,0.0001328466,0.00005725168,0.00009060476,0.00001086436,0.00002093729,0.00005783346,0.00001339768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000106581,"about_ca_system_score_gemma":0.0001670022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001233143,"about_ca_topic_score_gemma":0.00001079297,"domain_scores_codex":[0.9987709,0.00006338574,0.0003876745,0.0003492716,0.0001182931,0.0003105116],"domain_scores_gemma":[0.9991177,0.00000617848,0.0001636595,0.0003983619,0.000137749,0.0001763248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003107796,0.0001581502,0.0005337221,0.0000553489,0.00003982487,0.000001305662,0.000183544,0.000005080786,0.9928967,0.00002782407,0.002314515,0.00347315],"study_design_scores_gemma":[0.0006360264,0.0001115292,0.180445,0.00002686062,0.00002501747,9.538793e-7,0.00004365955,0.000004328596,0.8151048,0.00003810181,0.003386713,0.0001770086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963561,0.001644369,0.0002289662,0.0002983808,0.00009006982,0.0002378246,0.001056242,0.00002511842,0.0000629501],"genre_scores_gemma":[0.9977343,0.0005542334,0.0000934297,0.0007159097,0.0001154797,0.00001672454,0.0004408475,0.00001835146,0.0003107076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1799113,"threshold_uncertainty_score":0.7821541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005804796394919567,"score_gpt":0.2638674332056821,"score_spread":0.2580626368107626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}