{"id":"W1974571658","doi":"10.1371/journal.pone.0104315","title":"In Silico Insights into Protein-Protein Interactions and Folding Dynamics of the Saposin-Like Domain of Solanum tuberosum Aspartic Protease","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Plant Reproductive Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biochemistry; Hordeum vulgare; Protease; Protein structure; Biology; Protein folding; Solanum tuberosum; Biophysics; Energy landscape; Plant protein; Chemistry; Enzyme; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001878294,0.0001212138,0.0002167286,0.00005457217,0.00004289201,0.000005378452,0.0001591226,0.00009697532,0.000003796157],"category_scores_gemma":[0.000338223,0.000094636,0.00003865311,0.0001003742,0.0001802625,0.000007993186,0.0001845333,0.0001271675,0.000001280568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002597342,"about_ca_system_score_gemma":0.00003935903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001134361,"about_ca_topic_score_gemma":0.0006463604,"domain_scores_codex":[0.998973,0.0001917743,0.0002637605,0.0003154385,0.0001048171,0.0001511813],"domain_scores_gemma":[0.9992918,0.00001736256,0.0001615005,0.0004106419,0.00008091489,0.00003771329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001174924,0.0004350055,0.007883515,0.0001320081,0.00006765202,4.553478e-7,0.0001037551,0.000004045497,0.9904798,0.0006721047,0.000006785314,0.0000973323],"study_design_scores_gemma":[0.000350635,0.0002630155,0.003713932,0.0001817543,0.00002180638,0.000003646659,0.00003763227,0.0003299343,0.9924182,0.002423792,0.000146859,0.0001087489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981576,0.0001472572,0.0002678337,0.0004435319,0.00003902752,0.0008297383,0.00001003162,0.000004603365,0.0001003972],"genre_scores_gemma":[0.9983499,0.000007657744,0.001206654,0.00003392734,0.00006088197,0.0001217898,0.00002252241,0.00001224692,0.000184444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004169583,"threshold_uncertainty_score":0.3859144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0110340976798337,"score_gpt":0.2139545519341602,"score_spread":0.2029204542543265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}