{"id":"W1974571658","doi":"10.1371/journal.pone.0104315","title":"In Silico Insights into Protein-Protein Interactions and Folding Dynamics of the Saposin-Like Domain of Solanum tuberosum Aspartic Protease","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Plant Reproductive Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biochemistry; Hordeum vulgare; Protease; Protein structure; Biology; Protein folding; Solanum tuberosum; Biophysics; Energy landscape; Plant protein; Chemistry; Enzyme; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003165341,0.000638208,0.0006830439,0.0003104797,0.000393806,0.000519737,0.0004940347,0.000648448,0.0008557139],"category_scores_gemma":[0.0004426529,0.0003393363,0.0006279638,0.0002210934,0.0001680606,0.0003003156,0.0001997975,0.0003795843,0.0001948865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004341403,"about_ca_system_score_gemma":0.0005726211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002299994,"about_ca_topic_score_gemma":0.003417969,"domain_scores_codex":[0.9999204,0.0000248157,0.000004663025,0.00002063066,0.00001460105,0.00001499918],"domain_scores_gemma":[0.9998122,0.0001181391,0.00002377458,0.00001049708,0.00001616469,0.00001927255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0009827778,0.000503323,0.02572023,0.0002338415,0.0003279,0.0006880047,0.0001456757,0.8270838,0.1356091,0.001418293,0.0004665904,0.006820536],"study_design_scores_gemma":[0.00002346978,0.0000683019,0.002029907,0.00000247541,0.00002606623,0.00003506842,0.00002002803,0.9935917,0.003918268,0.0001514851,0.0001285373,0.000004580386],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936848,0.00008663435,0.005282676,0.00003704957,0.000005499171,0.00001259582,0.0002032981,0.0001796765,0.0005077789],"genre_scores_gemma":[0.9879686,0.0001204083,0.01052465,0.00002310798,0.000004217336,0.00003187247,0.001000799,0.00005343186,0.0002729304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002299994,"threshold_uncertainty_score":0.004573166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0110340976798337,"score_gpt":0.2139545519341602,"score_spread":0.2029204542543265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}