{"id":"W1974571784","doi":"10.1016/j.annder.2014.09.084","title":"Traitement par anticorps anti-PD-1 : pembrolizumab (MK-3475) chez 411 patients (pts) atteints de mélanome métastatique","year":2014,"lang":"fr","type":"article","venue":"Annales de Dermatologie et de Vénéréologie","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001669122,0.0005077336,0.0004374739,0.0003054369,0.0007843595,0.0008182178,0.0001462338,0.0006802295,0.001759995],"category_scores_gemma":[0.0008234869,0.0004130172,0.0004437421,0.0003450913,0.0003601568,0.0004452927,0.0001807556,0.000761889,0.0003541996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004166861,"about_ca_system_score_gemma":0.0003154871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004602423,"about_ca_topic_score_gemma":0.003728515,"domain_scores_codex":[0.9998257,0.00002733047,0.0000168261,0.00005832742,0.0000327332,0.00003912629],"domain_scores_gemma":[0.9997306,0.0001165246,0.00007366728,0.00001196739,0.00001767194,0.0000495029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.00535097,0.0005201059,0.8917286,0.00007501905,0.0002081463,0.04344324,0.001113534,0.001286147,0.02933213,0.0003301188,0.001023846,0.02558828],"study_design_scores_gemma":[0.0003267495,0.002687517,0.9282053,0.0000202766,0.0002504699,0.05581608,0.0006247109,0.001496734,0.006692159,0.0001224121,0.003718605,0.00003886469],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988217,0.0002792419,0.0001525415,0.00006937305,0.00001174515,0.000006779017,0.0001142258,0.000008418298,0.0005360793],"genre_scores_gemma":[0.998472,0.000279124,0.0001426072,0.00003874951,0.00002905126,0.000008338039,0.0001840997,0.000003155053,0.0008428508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004602423,"threshold_uncertainty_score":0.00915128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02833442453355193,"score_gpt":0.3155192893932378,"score_spread":0.2871848648596859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}