{"id":"W1974590591","doi":"10.1074/jbc.m509266200","title":"Expression Patterns and Post-translational Modifications Associated with Mammalian Histone H3 Variants","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":326,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of General Medical Sciences","keywords":"Histone H3; Biology; Chromatin; Histone; Heterochromatin; Heterochromatin protein 1; Regulation of gene expression; Gene silencing; Gene expression; Cell biology; Genetics; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328007,0.0001094861,0.0001336054,0.0000120042,0.00006016103,0.00001656685,0.0001112094,0.0001857416,0.00006318013],"category_scores_gemma":[0.00007025622,0.00007694436,0.00005777785,0.00002715793,0.00006554811,0.000004970771,0.00003163894,0.000130196,4.989329e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001982059,"about_ca_system_score_gemma":0.00004937685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001012341,"about_ca_topic_score_gemma":0.000002979063,"domain_scores_codex":[0.9993461,0.00002302723,0.00025744,0.0001486303,0.00009938257,0.0001253681],"domain_scores_gemma":[0.9993899,0.00001720326,0.0002398676,0.000106164,0.000149332,0.00009756383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007445262,0.0001183793,0.004905201,0.000006897973,0.00003487786,0.000006531495,0.00002083313,0.0001172156,0.9940727,0.000006035859,0.00008671035,0.0005501503],"study_design_scores_gemma":[0.002212916,0.0006760876,0.3555149,0.0001060398,0.0000636012,0.0008165904,0.0001750131,0.0006639934,0.6366851,0.0001494295,0.002462532,0.0004738516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975671,0.0002685266,0.001354334,0.0004259076,0.00001701344,0.00003526708,0.0000685541,0.000003477817,0.000259855],"genre_scores_gemma":[0.9971043,0.0001109475,0.002160617,0.00009669695,0.0001794843,0.000001872569,0.0001470572,0.000008026288,0.000190925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3573877,"threshold_uncertainty_score":0.31377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01148713748754365,"score_gpt":0.2359190389858473,"score_spread":0.2244319014983036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}