{"id":"W1974628404","doi":"10.4161/cib.24298","title":"Ras GTPases’ interaction with effector domains","year":2013,"lang":"en","type":"article","venue":"Communicative & Integrative Biology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"GTPase; Rab; Biology; Effector; Computational biology; CDC42; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001618386,0.0002593404,0.0002468142,0.0000722503,0.000173152,0.00003010572,0.0003992133,0.0001701338,0.0003696819],"category_scores_gemma":[0.0001818882,0.0001728249,0.00009834858,0.0001331736,0.0005117171,0.00001373136,0.0002156123,0.0002702188,0.0001563289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004816407,"about_ca_system_score_gemma":0.00005793585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001807228,"about_ca_topic_score_gemma":0.0001832629,"domain_scores_codex":[0.9984831,0.0006402243,0.000225838,0.0003456234,0.00006009606,0.0002451842],"domain_scores_gemma":[0.9985548,0.0001165319,0.0001866318,0.0007111208,0.0003396405,0.00009131168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002272655,0.0001184191,0.00437406,0.000007057128,0.0001791546,9.41389e-7,0.000277987,0.000006214083,0.9796039,0.004699813,0.001572934,0.008932288],"study_design_scores_gemma":[0.001589426,0.002408443,0.01057191,0.0001376045,0.00003634629,0.00003944592,0.001962627,0.000237847,0.8525323,0.001607611,0.128251,0.0006254286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9566136,0.001665175,0.02697681,0.0006725546,0.0001022609,0.0009677329,0.00003648415,0.00005315443,0.01291221],"genre_scores_gemma":[0.9939829,0.00014175,0.004045469,0.0004540313,0.0001102143,0.0003889459,0.0005460205,0.00002372897,0.0003069064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1270715,"threshold_uncertainty_score":0.7047597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01333580689270237,"score_gpt":0.2863826034038003,"score_spread":0.273046796511098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}