{"id":"W1974633849","doi":"10.1016/j.bmc.2008.04.029","title":"E,E-2-Benzylidene-6-(nitrobenzylidene)cyclohexanones: Syntheses, cytotoxicity and an examination of some of their electronic, steric, and hydrophobic properties","year":2008,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Steric effects; Cytotoxicity; Stereochemistry; Aryl; Cytotoxic T cell; In vitro; Biochemistry; Organic chemistry; Alkyl","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000939494,0.0001523266,0.0001654777,0.0002145035,0.0001571258,0.0001388121,0.0001453203,0.000120357,0.003440922],"category_scores_gemma":[0.0001046013,0.0000799537,0.00009311218,0.0001730243,0.0001659005,0.0002712782,0.0001588914,0.0002426346,0.000835175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001766286,"about_ca_system_score_gemma":0.0001893063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005529818,"about_ca_topic_score_gemma":0.000973266,"domain_scores_codex":[0.999938,0.00001240721,0.000005446991,0.000007708134,0.00001421138,0.00002224876],"domain_scores_gemma":[0.9999529,0.00001124967,0.0000109883,0.000008210836,0.00000724337,0.000009429566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005384592,0.0001661245,0.0005974744,0.0001909889,0.000007893457,0.0003351854,0.00006487796,0.000534446,0.9761897,0.001447093,0.0002514544,0.01967619],"study_design_scores_gemma":[0.00002965987,0.0008212166,0.003538394,0.00001713255,0.000009560139,0.0003864825,0.00005781194,0.0003765301,0.9865725,0.0001774413,0.008003982,0.000009338874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9580294,0.00886776,0.005704253,0.0002777739,0.0001306712,0.00006988874,0.000626446,0.0001040823,0.02618973],"genre_scores_gemma":[0.9812692,0.005734114,0.002142227,0.00009458342,0.00002921121,0.00004422289,0.0003915669,0.00001718138,0.01027755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003440922,"threshold_uncertainty_score":0.01151103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02788381392493481,"score_gpt":0.2136217540718096,"score_spread":0.1857379401468748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}