{"id":"W1974633849","doi":"10.1016/j.bmc.2008.04.029","title":"E,E-2-Benzylidene-6-(nitrobenzylidene)cyclohexanones: Syntheses, cytotoxicity and an examination of some of their electronic, steric, and hydrophobic properties","year":2008,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Steric effects; Cytotoxicity; Stereochemistry; Aryl; Cytotoxic T cell; In vitro; Biochemistry; Organic chemistry; Alkyl","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000340002,0.0003197698,0.0006272097,0.00003433799,0.0001142357,0.00001078625,0.0002605745,0.0002957039,0.0003619048],"category_scores_gemma":[0.000284322,0.0002255167,0.0000673641,0.0001134054,0.00068867,0.00018008,0.0001357606,0.0002576062,7.031917e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007606123,"about_ca_system_score_gemma":0.0001165136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001068692,"about_ca_topic_score_gemma":0.000005365077,"domain_scores_codex":[0.9982804,0.00006054294,0.0004867185,0.0004917026,0.0003271539,0.0003534508],"domain_scores_gemma":[0.9987994,0.0002298834,0.0003420047,0.0003655447,0.00009879377,0.0001643422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001105721,0.0002590041,0.00340615,0.000572012,0.00005544065,0.000007500958,0.0003037771,1.056797e-7,0.9924466,0.000009744703,0.000004309858,0.002824753],"study_design_scores_gemma":[0.0003320416,0.0001550194,0.01358396,0.0002285569,0.00005040977,0.0002138165,0.0008306953,0.00006955431,0.9841516,0.0000784224,0.00005810887,0.000247829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950218,0.004075589,0.00000557604,0.00004568951,0.0000130638,0.00008578345,0.00003130798,0.00005257257,0.0006686006],"genre_scores_gemma":[0.9979165,0.001662542,0.00003064472,0.00002437604,0.0002060749,0.00001282672,0.00001205778,0.00002585214,0.000109185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01017781,"threshold_uncertainty_score":0.9196303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02788381392493481,"score_gpt":0.2136217540718096,"score_spread":0.1857379401468748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}