{"id":"W1974656051","doi":"10.1038/sj.ki.5000136","title":"PAX2 inactivation enhances cisplatin-induced apoptosis in renal carcinoma cells","year":2006,"lang":"en","type":"article","venue":"Kidney International","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"","keywords":"Apoptosis; Cisplatin; Biology; Cancer research; Kidney; Gene knockdown; Transfection; Molecular biology; Cell culture; Endocrinology; Chemotherapy; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002099632,0.0002892576,0.0004035519,0.0004263196,0.0003091472,0.000425552,0.0002852303,0.0003451092,0.00352345],"category_scores_gemma":[0.0002022515,0.0002216189,0.0003168563,0.000448275,0.0002597418,0.0004278691,0.000266671,0.0008793017,0.0004467951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003463768,"about_ca_system_score_gemma":0.0003981639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001171078,"about_ca_topic_score_gemma":0.001478182,"domain_scores_codex":[0.9997515,0.00005066647,0.00002302296,0.00003252404,0.00008540526,0.00005683377],"domain_scores_gemma":[0.9998834,0.00003294181,0.00001528564,0.00002361551,0.00001572835,0.00002907418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005337051,0.0001246246,0.0006223038,0.00005423469,0.00002488224,0.0001401705,0.00004504745,0.0002362164,0.9950906,0.0004874951,0.0001824685,0.002458258],"study_design_scores_gemma":[0.00003713634,0.0003783961,0.003803082,0.000003790577,0.00002169567,0.0002692558,0.00005591059,0.001378209,0.9916333,0.00006565737,0.002349016,0.000004502795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931746,0.001122555,0.001646733,0.0001442997,0.00005867597,0.00003899206,0.0002855783,0.00009523741,0.003433203],"genre_scores_gemma":[0.9963208,0.0003446574,0.0005165345,0.000025438,0.000006891948,0.00003150822,0.0003065596,0.000009648509,0.002437924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00352345,"threshold_uncertainty_score":0.01178706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005377727655724618,"score_gpt":0.2242322012324469,"score_spread":0.2188544735767222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}