{"id":"W1974665005","doi":"10.1016/s0378-1119(00)00302-4","title":"Sp1 and Sp3 transactivate the RET proto-oncogene promoter","year":2000,"lang":"en","type":"article","venue":"Gene","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Transactivation; Biology; Neural crest; Promoter; Molecular biology; Transcription factor; Footprinting; DNA footprinting; Luciferase; Transcription (linguistics); Response element; DNA-binding protein; Cell culture; Cell biology; Transfection; Gene expression; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009948573,0.0001069689,0.0000765818,0.00000749276,0.00008587684,0.00002559093,0.0001276505,0.0000798768,0.0001143506],"category_scores_gemma":[0.000002902502,0.00007649024,0.00004142139,0.0000317503,0.00005575554,0.00000138976,0.000023758,0.00005443722,0.00001391262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004943998,"about_ca_system_score_gemma":0.00002503168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007675188,"about_ca_topic_score_gemma":0.00001203277,"domain_scores_codex":[0.9994169,0.00002594859,0.0001121708,0.0002191879,0.0000592221,0.0001665849],"domain_scores_gemma":[0.9996271,0.000002250252,0.00002535384,0.0002838998,0.0000164257,0.00004495718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004215381,0.00002304145,0.0001841172,0.000009700148,0.00003103078,0.00000217231,0.00008930227,0.00004442278,0.9682454,0.000007876015,0.0001860548,0.03113469],"study_design_scores_gemma":[0.0005678823,0.0002324131,0.001960565,0.000006174397,0.00002205356,0.00009313786,0.00002355149,0.000482245,0.8961141,0.0003541333,0.09992063,0.0002231001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971699,0.0003854356,0.0003000385,0.0004023106,0.00003153607,0.0003828988,0.00002228476,0.000006941932,0.001298702],"genre_scores_gemma":[0.995679,0.0004258773,0.00115655,0.0003128316,0.0001507245,0.00005267984,0.00004285323,0.00002035316,0.002159128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09973458,"threshold_uncertainty_score":0.3119181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003968612472087771,"score_gpt":0.1928907769362448,"score_spread":0.188922164464157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}