{"id":"W1974665005","doi":"10.1016/s0378-1119(00)00302-4","title":"Sp1 and Sp3 transactivate the RET proto-oncogene promoter","year":2000,"lang":"en","type":"article","venue":"Gene","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Transactivation; Biology; Neural crest; Promoter; Molecular biology; Transcription factor; Footprinting; DNA footprinting; Luciferase; Transcription (linguistics); Response element; DNA-binding protein; Cell culture; Cell biology; Transfection; Gene expression; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002321545,0.0004114015,0.0001955177,0.0004980144,0.0002931595,0.0003910974,0.0003526063,0.0003998941,0.002641893],"category_scores_gemma":[0.0002427144,0.0003509182,0.0004961461,0.0002309194,0.0003511276,0.00028042,0.0004343929,0.0009139386,0.001125962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007783355,"about_ca_system_score_gemma":0.0002827408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00201375,"about_ca_topic_score_gemma":0.003568657,"domain_scores_codex":[0.999768,0.00003774471,0.000008924534,0.00004649033,0.00006516622,0.00007373259],"domain_scores_gemma":[0.9997621,0.0000890906,0.00002960004,0.00003023394,0.00003050771,0.00005850187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001026292,0.00001101326,0.000115795,0.00001248348,0.000003290867,0.00003007905,0.00001981753,0.00004038144,0.9984196,0.0003035108,0.00003968671,0.0009016635],"study_design_scores_gemma":[0.0000223284,0.00006789764,0.004166688,0.000005463748,0.000009361034,0.0002499922,0.00005482479,0.001265268,0.990999,0.0003008533,0.002853148,0.000005239694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855134,0.002035548,0.007212452,0.000247948,0.00005932371,0.00002426518,0.0004516098,0.0002115711,0.004243892],"genre_scores_gemma":[0.9841209,0.0006401546,0.003379364,0.00008073275,0.00002388521,0.00002351481,0.001069594,0.000113343,0.01054847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002641893,"threshold_uncertainty_score":0.008837998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003968612472087771,"score_gpt":0.1928907769362448,"score_spread":0.188922164464157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}