{"id":"W1974672667","doi":"10.1159/000358636","title":"PPARγ-Induced Stimulation of Amiloride-Sensitive Sodium Current in Renal Collecting Duct Principal Cells is Serum and Insulin Dependent","year":2014,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Institut National de la Santé et de la Recherche Médicale; Kidney Foundation of Canada","keywords":"Epithelial sodium channel; SGK1; Rosiglitazone; Endocrinology; Internal medicine; Amiloride; Renal sodium reabsorption; Pioglitazone; Aldosterone; Chemistry; Insulin; Reabsorption; Medicine; Type 2 diabetes; Kidney; Sodium; Diabetes mellitus; Glucocorticoid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001646528,0.0001662721,0.0002028984,0.00003708489,0.00006733285,0.000005763042,0.00005820148,0.0002395253,0.000005796054],"category_scores_gemma":[0.00001782526,0.0001651925,0.00004571725,0.00006513858,0.0001034096,0.000004584384,0.0000569958,0.0001291097,7.227645e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001019771,"about_ca_system_score_gemma":0.00003857968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001370172,"about_ca_topic_score_gemma":0.000006473597,"domain_scores_codex":[0.999032,0.00004922018,0.0002537357,0.0004013261,0.00007818158,0.0001855954],"domain_scores_gemma":[0.9995716,0.00001575681,0.0001308308,0.0001578959,0.00006710052,0.00005677011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001646691,0.00005491473,0.002766082,0.0001190282,0.00001880474,0.000001088219,0.00009899383,0.00006664427,0.9955058,0.000007694352,0.000008524846,0.00118777],"study_design_scores_gemma":[0.0008120721,0.0001177046,0.0152358,0.00003490072,0.00001852859,0.000004673613,0.00005839885,0.001267486,0.9821075,0.0001054388,0.00007515267,0.0001623275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999046,0.0004119852,0.0002132262,0.00002214046,0.0001179013,0.0001185708,0.00001515668,0.000005595179,0.00004947777],"genre_scores_gemma":[0.9992889,0.0001472857,0.00005745519,0.00002403509,0.000212955,0.000005686056,0.0001863191,0.00001080337,0.00006657509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01339827,"threshold_uncertainty_score":0.6736354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01052945351328346,"score_gpt":0.228784040510336,"score_spread":0.2182545869970525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}