{"id":"W1974672667","doi":"10.1159/000358636","title":"PPARγ-Induced Stimulation of Amiloride-Sensitive Sodium Current in Renal Collecting Duct Principal Cells is Serum and Insulin Dependent","year":2014,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Institut National de la Santé et de la Recherche Médicale; Kidney Foundation of Canada","keywords":"Epithelial sodium channel; SGK1; Rosiglitazone; Endocrinology; Internal medicine; Amiloride; Renal sodium reabsorption; Pioglitazone; Aldosterone; Chemistry; Insulin; Reabsorption; Medicine; Type 2 diabetes; Kidney; Sodium; Diabetes mellitus; Glucocorticoid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002051068,0.0002416999,0.0004271344,0.0002453183,0.0002356745,0.0003176781,0.0002069848,0.0002687671,0.002317749],"category_scores_gemma":[0.0001411975,0.0001571297,0.0008731085,0.0002934154,0.0002937997,0.0002665915,0.0002479727,0.0006878217,0.0004938007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003959759,"about_ca_system_score_gemma":0.0003746597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009416223,"about_ca_topic_score_gemma":0.001602019,"domain_scores_codex":[0.9997469,0.00002818942,0.00004190912,0.00007061479,0.00007013672,0.00004229271],"domain_scores_gemma":[0.999823,0.00002117742,0.00004837844,0.00003000536,0.00004678761,0.00003054206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003518514,0.00003089887,0.0003554911,0.0001211363,0.00001286413,0.00008878568,0.00003091853,0.00001527252,0.9977876,0.00004639505,0.00007213235,0.001086679],"study_design_scores_gemma":[0.00006938956,0.0004381859,0.02871159,0.00002336553,0.00006114392,0.0005204944,0.0001342506,0.0003913105,0.9632878,0.00009369096,0.006256605,0.00001227745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815381,0.00807698,0.004797124,0.0006410431,0.0002173334,0.00006587835,0.001566591,0.00021142,0.002885507],"genre_scores_gemma":[0.9876485,0.003668878,0.00251725,0.0002610229,0.00005151495,0.0000890676,0.00120159,0.00002082101,0.004541324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002317749,"threshold_uncertainty_score":0.00775367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01052945351328346,"score_gpt":0.228784040510336,"score_spread":0.2182545869970525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}