{"id":"W1974708712","doi":"10.1371/journal.pone.0050561","title":"Mouse Nkrp1-Clr Gene Cluster Sequence and Expression Analyses Reveal Conservation of Tissue-Specific MHC-Independent Immunosurveillance","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre; University of Ottawa","funders":"Ontario Ministry of Research and Innovation; Canadian Institutes of Health Research; National Cancer Institute; U.S. Department of Health and Human Services; National Institutes of Health; Frederick National Laboratory for Cancer Research; University of Ottawa; Burroughs Wellcome Fund","keywords":"Biology; Pseudogene; Gene; Genetics; Immunosurveillance; Major histocompatibility complex; Phenotype; Gene family; Haplotype; Gene expression; Immune system; Allele; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002654587,0.0001389821,0.0002782869,0.00009704696,0.0001163512,0.00001231672,0.00009022788,0.0001717781,0.0007515688],"category_scores_gemma":[0.00006360467,0.0001255841,0.00003831297,0.00008542273,0.0001040874,0.0002901244,0.00006656078,0.0002061295,0.0002244847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004278521,"about_ca_system_score_gemma":0.00001203714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007939031,"about_ca_topic_score_gemma":0.000003515253,"domain_scores_codex":[0.9989175,0.0002309413,0.0003574598,0.0001936008,0.00007188585,0.0002286486],"domain_scores_gemma":[0.9992194,0.0001061352,0.0002267857,0.000277118,0.0001479187,0.00002270986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002912502,0.000471238,0.008763237,0.0000393315,0.0001385498,2.841167e-7,0.0003143411,0.000001194985,0.985608,0.00001059076,0.004045845,0.000316127],"study_design_scores_gemma":[0.0006452109,0.0001226595,0.01424831,0.00007208186,0.00004111684,0.00001730454,0.0001240442,0.000007702693,0.9783899,0.000003008047,0.006197278,0.0001314456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924635,0.005988994,0.000260335,0.0001273645,0.0004866685,0.0002197505,0.00001411165,0.00004633805,0.0003929165],"genre_scores_gemma":[0.9886519,0.0007917046,0.0004251657,0.000144991,0.00004899318,0.00001830091,0.0002111431,0.00001452589,0.009693232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009300316,"threshold_uncertainty_score":0.8229151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.098191488319885,"score_gpt":0.2855177050867961,"score_spread":0.1873262167669111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}