{"id":"W1974709141","doi":"10.1046/j.1365-2958.2001.02240.x","title":"Genetic and transcriptional analysis of <i>absA</i>, an antibiotic gene cluster‐linked two‐component system that regulates multiple antibiotics in <i>Streptomyces coelicolor</i>","year":2001,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"TerraBioGen (Canada)","funders":"","keywords":"Streptomyces coelicolor; Biology; Antibiotics; Gene; Gene cluster; Genetics; Component (thermodynamics); Streptomyces; Cluster (spacecraft); Computational biology; Microbiology; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001074337,0.0005002696,0.0001858433,0.0002625868,0.0001657884,0.0002441748,0.0001838587,0.0001672489,0.0005398476],"category_scores_gemma":[0.0001502837,0.0001414749,0.0002832278,0.0002184161,0.0002394279,0.000124785,0.0002067333,0.0004909199,0.0003437089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005896832,"about_ca_system_score_gemma":0.0003299539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001866864,"about_ca_topic_score_gemma":0.002274271,"domain_scores_codex":[0.9998481,0.00002673771,0.00001186814,0.00002390608,0.00005511962,0.00003417996],"domain_scores_gemma":[0.9998035,0.0000461933,0.00005195396,0.0000208773,0.00001987921,0.00005760297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003850201,0.00001567718,0.0001184031,0.00001472461,0.00000164855,0.0000304795,0.00000812206,0.00006658478,0.9992303,0.00008447785,0.000009808338,0.0003812031],"study_design_scores_gemma":[0.00001191327,0.0001634685,0.008078926,0.000005238704,0.00001290803,0.0002574788,0.00003470767,0.001535288,0.9879755,0.00007534305,0.001842743,0.000006329156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942437,0.0004048106,0.003126472,0.00009038447,0.00001957976,0.00002548478,0.0008217801,0.00008168485,0.001186138],"genre_scores_gemma":[0.9903997,0.0002931629,0.00379892,0.00004290567,0.00001260926,0.00002649525,0.002727728,0.00005704513,0.002641427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001866864,"threshold_uncertainty_score":0.004278481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01188122872340571,"score_gpt":0.2315454999313036,"score_spread":0.2196642712078979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}