{"id":"W1974722772","doi":"10.1111/j.0022-202x.2005.23692.x","title":"Transfer of CD8+ Cells Induces Localized Hair Loss Whereas CD4+/CD25− Cells Promote Systemic Alopecia Areata and CD4+/CD25+ Cells Blockade Disease Onset in the C3H/HeJ Mouse Model","year":2005,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":159,"is_retracted":false,"has_abstract":false,"ca_institutions":"Okanagan University College; University of British Columbia","funders":"Deutsche Forschungsgemeinschaft; National Alopecia Areata Foundation","keywords":"IL-2 receptor; CD8; Hair loss; Adoptive cell transfer; Endocrinology; Hair follicle; Alopecia areata; CD80; Immunology; Cytotoxic T cell; CD40; T cell; Biology; Internal medicine; Medicine; Antigen; In vitro; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005519526,0.0004379883,0.000991155,0.000437351,0.0001740432,0.00003586124,0.0005296523,0.0004508451,0.0001738376],"category_scores_gemma":[0.0001099658,0.0003168059,0.0002468035,0.0002502635,0.001149029,0.0005390042,0.000067848,0.00118523,0.00008771761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001104946,"about_ca_system_score_gemma":0.000349058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007497882,"about_ca_topic_score_gemma":0.00005659629,"domain_scores_codex":[0.9960582,0.001435795,0.001499225,0.0003653003,0.0001532717,0.000488168],"domain_scores_gemma":[0.9980768,0.0003642334,0.0006976693,0.0003838813,0.0003426254,0.0001347779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009433085,0.0004348311,0.0002750832,0.0001604145,0.0002915027,0.00009391757,0.004894749,0.001634763,0.9792443,0.0001840636,0.01165262,0.0001904272],"study_design_scores_gemma":[0.003170596,0.0002288905,0.0002154023,0.0003199724,0.0002172406,0.001555413,0.001679187,0.0009567555,0.9812242,0.0002525109,0.009874912,0.0003048997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991406,0.00319594,0.0005555141,0.00333266,0.0007462925,0.0005265058,0.00008212051,0.00002113215,0.0001338912],"genre_scores_gemma":[0.9963383,0.0007434341,0.0002199472,0.00137764,0.00004910809,0.00002048511,0.00003772118,0.00003488631,0.001178466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004932369,"threshold_uncertainty_score":0.9999284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01732041075858874,"score_gpt":0.2311327490426174,"score_spread":0.2138123382840287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}