{"id":"W1974722772","doi":"10.1111/j.0022-202x.2005.23692.x","title":"Transfer of CD8+ Cells Induces Localized Hair Loss Whereas CD4+/CD25− Cells Promote Systemic Alopecia Areata and CD4+/CD25+ Cells Blockade Disease Onset in the C3H/HeJ Mouse Model","year":2005,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":159,"is_retracted":false,"has_abstract":false,"ca_institutions":"Okanagan University College; University of British Columbia","funders":"Deutsche Forschungsgemeinschaft; National Alopecia Areata Foundation","keywords":"IL-2 receptor; CD8; Hair loss; Adoptive cell transfer; Endocrinology; Hair follicle; Alopecia areata; CD80; Immunology; Cytotoxic T cell; CD40; T cell; Biology; Internal medicine; Medicine; Antigen; In vitro; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002276097,0.001148609,0.00049026,0.0009188701,0.0003739909,0.0005456289,0.0003208579,0.0007209362,0.00282174],"category_scores_gemma":[0.0001541608,0.000351786,0.0005044828,0.0001988038,0.0005299887,0.0004537186,0.0003042812,0.002457652,0.0008049982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004577723,"about_ca_system_score_gemma":0.0002819228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008383536,"about_ca_topic_score_gemma":0.001911261,"domain_scores_codex":[0.9994647,0.00007043601,0.00003698668,0.000107464,0.0001081899,0.0002123121],"domain_scores_gemma":[0.9995788,0.00005173746,0.0001018621,0.00005414635,0.00002290699,0.0001905343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002417255,0.0001732276,0.0001287447,0.00002677964,0.000006405665,0.0001153315,0.00001718109,0.0000606731,0.9983264,0.0001082467,0.00006369818,0.0007316888],"study_design_scores_gemma":[0.0001605068,0.001647039,0.0067231,0.00002090158,0.00004684945,0.0006414737,0.00008902469,0.001309169,0.987555,0.0001374814,0.001658151,0.0000113846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955772,0.0007059927,0.001059721,0.0001303804,0.00006708101,0.00004720458,0.0002684743,0.0002077143,0.001936333],"genre_scores_gemma":[0.991837,0.0003991289,0.001087104,0.00009225066,0.00004733908,0.00005727864,0.0003202812,0.00005603204,0.006103724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00282174,"threshold_uncertainty_score":0.009439647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01732041075858874,"score_gpt":0.2311327490426174,"score_spread":0.2138123382840287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}