{"id":"W1974754172","doi":"10.1038/ng1644","title":"Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates","year":2005,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":552,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"Wellcome Trust","keywords":"Convergent extension; Biology; Zebrafish; Cell polarity; Cilium; Cell biology; Frizzled; Phenotype; Genetics; Wnt signaling pathway; Neurulation; Axoneme; Gastrulation; Mutant; Gene; Genetic screen; Bardet–Biedl syndrome; Cell; Flagellum; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001180023,0.0002128057,0.0002056305,0.00007603802,0.00004134487,0.00001331762,0.0002643254,0.0005573367,0.00003296152],"category_scores_gemma":[0.00007065284,0.0002055895,0.0001040925,0.0001310892,0.00007449477,0.000003998998,0.00007755727,0.00027737,0.0000128925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002193777,"about_ca_system_score_gemma":0.0001577423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001585427,"about_ca_topic_score_gemma":0.00007254446,"domain_scores_codex":[0.9987488,0.00006660449,0.000283059,0.0003851892,0.0002228923,0.0002934753],"domain_scores_gemma":[0.9992555,0.000008644982,0.00008606202,0.0004186946,0.00008515563,0.0001459461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001151758,0.0003743521,0.04656596,0.0001217068,0.00003292726,0.00001354857,0.00009579259,0.0001961211,0.9497394,0.000008140064,0.00155785,0.001179023],"study_design_scores_gemma":[0.001183118,0.0005661524,0.2422418,0.00003711936,0.00005010925,0.0000403819,0.0001156654,0.0003578681,0.7368973,0.0001579964,0.01793152,0.0004208947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841365,0.01417822,0.0001149609,0.0002247401,0.000123104,0.0003333682,0.0001739936,0.00001086867,0.0007043049],"genre_scores_gemma":[0.9948219,0.0005978264,0.003261266,0.0004531195,0.0001716448,0.00001731234,0.000322487,0.00002701635,0.0003274413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.212842,"threshold_uncertainty_score":0.8383697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00402847792014175,"score_gpt":0.2251270381027176,"score_spread":0.2210985601825759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}