{"id":"W1974840376","doi":"10.1186/1471-2407-14-166","title":"Sunitinib in combination with trastuzumab for the treatment of advanced breast cancer: activity and safety results from a phase II study","year":2014,"lang":"en","type":"article","venue":"BMC Cancer","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre de Santé et de Services Sociaux de Chicoutimi; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Pfizer","keywords":"Medicine; Trastuzumab; Tolerability; Sunitinib; Internal medicine; Adverse effect; Lapatinib; Breast cancer; Oncology; Clinical endpoint; Metastatic breast cancer; Cancer; Surgery; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003183154,0.0001543354,0.0003824414,0.00007005495,0.0001147192,0.000009753926,0.00007382997,0.00004216011,0.0000599846],"category_scores_gemma":[0.00005738706,0.00009589489,0.00003857246,0.0002150537,0.0001095103,0.00006418712,0.00001895809,0.0001000646,2.390287e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006729497,"about_ca_system_score_gemma":0.0004732537,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.02457978,"about_ca_topic_score_gemma":0.07143072,"domain_scores_codex":[0.9987534,0.0001083261,0.0002464028,0.0003448648,0.0003166743,0.0002303411],"domain_scores_gemma":[0.9986557,0.000635425,0.0001260336,0.0003393734,0.000161648,0.00008181957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.06019989,0.005274693,0.04116595,0.00009578439,0.0001845288,0.000002996674,0.006479692,0.0003122925,0.002072665,0.00001616204,0.0001060855,0.8840892],"study_design_scores_gemma":[0.131625,0.02038639,0.8234767,0.0004582689,0.0002839626,0.000004419491,0.002080636,0.005483508,0.005121816,0.00002643271,0.01084719,0.0002056132],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927698,0.000510447,0.0002714782,0.001592676,0.00008203199,0.003096666,0.001553357,0.00001587086,0.0001076138],"genre_scores_gemma":[0.996959,0.0009030519,0.0001457912,0.00002925829,0.000138176,0.00152125,0.00003281513,0.00002455368,0.0002461087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8838837,"threshold_uncertainty_score":0.9819157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05524808339423454,"score_gpt":0.404221311925435,"score_spread":0.3489732285312005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}