{"id":"W1974896569","doi":"10.1186/cc14060","title":"Early phases of sepsis: effects of simvastatin on mitochondrial enzyme activities in kidney tissue in rats","year":2014,"lang":"en","type":"article","venue":"Critical Care","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Children's Health Foundation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina; Financiadora de Estudos e Projetos; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Japan Society for the Promotion of Science; Russian Foundation for Basic Research; London Health Sciences Centre","keywords":"Simvastatin; Medicine; Kidney; Sepsis; Pharmacology; Enzyme; Acute kidney injury; Bioinformatics; Intensive care medicine; Internal medicine; Physiology; Biochemistry; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004079861,0.0008128936,0.0008681998,0.000889373,0.0003919549,0.0003105001,0.0003747031,0.0006568447,0.002101324],"category_scores_gemma":[0.0003004167,0.0004518754,0.0009676071,0.0004692658,0.0007521213,0.0008009178,0.0003884903,0.001910064,0.0004265688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004740427,"about_ca_system_score_gemma":0.0008700076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00175068,"about_ca_topic_score_gemma":0.002699932,"domain_scores_codex":[0.9996878,0.00004787614,0.00003808329,0.00005804306,0.00003854856,0.0001297417],"domain_scores_gemma":[0.9994702,0.00003582174,0.0001168338,0.00005837456,0.0000657473,0.000252943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.04409148,0.004985284,0.003140131,0.0002375487,0.00009495912,0.0003078392,0.0002359799,0.0002887007,0.9395984,0.0002465247,0.0002922844,0.006480796],"study_design_scores_gemma":[0.001127078,0.03165223,0.02056103,0.00002626633,0.0002752854,0.0002346538,0.0003780404,0.001419516,0.9422497,0.0003050825,0.001714827,0.0000562952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958947,0.001883521,0.0008624673,0.0002505757,0.00009891362,0.00004893508,0.0003939196,0.00005565351,0.0005113213],"genre_scores_gemma":[0.9919774,0.002261044,0.001490389,0.0001406944,0.00004755625,0.0001302766,0.0006467258,0.00001863763,0.003287383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002101324,"threshold_uncertainty_score":0.007029653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01130775781488122,"score_gpt":0.3061016790809757,"score_spread":0.2947939212660944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}