{"id":"W1974973003","doi":"10.1371/journal.pone.0107149","title":"Fatty Acid Esters of Phloridzin Induce Apoptosis of Human Liver Cancer Cells through Altered Gene Expression","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Atlantic Canada Opportunities Agency; Faculty of Medicine, Dalhousie University; Dalhousie University","keywords":"Phloretin; Cancer cell; Biochemistry; Apoptosis; Chemistry; Biology; Molecular biology; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001963555,0.0001824384,0.0004116656,0.00005679547,0.0001233653,0.000006089872,0.0002742356,0.0001977385,0.0008207913],"category_scores_gemma":[0.00001502627,0.0001692664,0.00009107259,0.0001140735,0.0002110436,0.0001209282,0.000122416,0.0003237961,0.00001982642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000332374,"about_ca_system_score_gemma":0.00002255659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000846551,"about_ca_topic_score_gemma":0.000007189001,"domain_scores_codex":[0.9986576,0.0002493696,0.0003418047,0.0002715831,0.0002148239,0.0002648173],"domain_scores_gemma":[0.9991494,0.00008869499,0.0003074986,0.0002273766,0.0001325341,0.00009445797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000149159,0.001942438,0.0126537,0.0002639649,0.0003267027,9.201338e-7,0.0007198495,0.000009761753,0.9826039,0.00005669666,0.0006669295,0.0006059947],"study_design_scores_gemma":[0.001081319,0.0001982827,0.003062349,0.0001573569,0.0002835645,2.518207e-7,0.00004054162,0.0001446179,0.9944237,0.00006279641,0.0003723811,0.0001728611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976723,0.0002982898,0.0001775766,0.00009626356,0.0003626514,0.0002516324,0.0001017536,0.00002543504,0.001014111],"genre_scores_gemma":[0.9969378,0.0005906544,0.001608555,0.0004008814,0.0002569182,0.0000323347,0.00001768754,0.00002208186,0.0001330919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01181979,"threshold_uncertainty_score":0.8987089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2589636743971476,"score_gpt":0.3984888751547728,"score_spread":0.1395252007576252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}