{"id":"W1974995243","doi":"10.1074/jbc.275.2.1145","title":"Expression, Purification, and Characterization of Natural Mutants of Human Aldolase B","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Diet, Metabolism, and Disease","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Aldolase A; Aldolase B; Fructose-bisphosphate aldolase; Biochemistry; Mutant; Isozyme; Biology; Phosphofructokinase 2; Fructose; Enzyme; Gene; Chemistry; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002527543,0.0003173711,0.0002060813,0.0001865811,0.000169435,0.0003027104,0.0002458964,0.0002847416,0.0003582443],"category_scores_gemma":[0.000364084,0.0001874988,0.0002180453,0.000259079,0.0002154156,0.0001670892,0.0001993606,0.0003959344,0.0003749306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002962462,"about_ca_system_score_gemma":0.0001863805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009793675,"about_ca_topic_score_gemma":0.0006811133,"domain_scores_codex":[0.9998154,0.00004193222,0.0000309292,0.00004135834,0.00004705789,0.00002327365],"domain_scores_gemma":[0.9998345,0.00003229381,0.0000314824,0.00003168478,0.00002952017,0.00004046034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008884289,0.00004372031,0.0005456699,0.00003272767,0.000009903936,0.00007800174,0.00003074782,0.0001480535,0.9975473,0.0001836634,0.00008321697,0.001208195],"study_design_scores_gemma":[0.0000512255,0.0002107909,0.007312978,0.00001067901,0.00003347955,0.002178211,0.000071973,0.002230659,0.9792671,0.0001755705,0.008444868,0.00001227381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927113,0.0009911299,0.004846876,0.0001664666,0.00002397692,0.00003509403,0.0008113639,0.00003720558,0.0003765505],"genre_scores_gemma":[0.980753,0.001186061,0.01126575,0.00007894516,0.00001912571,0.00004410072,0.00506485,0.00005406411,0.001534052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009793675,"threshold_uncertainty_score":0.002149463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01763857766294161,"score_gpt":0.2728143297000383,"score_spread":0.2551757520370966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}