{"id":"W1975039978","doi":"10.1074/jbc.m807607200","title":"Distinct Recruitment of Eps15 via Its Coiled-coil Domain Is Required For Efficient Down-regulation of the Met Receptor Tyrosine Kinase","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Liver physiology and pathology","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Coiled coil; Receptor tyrosine kinase; Tyrosine kinase; Tyrosine; Cell biology; Domain (mathematical analysis); Protein kinase domain; Receptor; ROR1; Tropomyosin receptor kinase C; Chemistry; Biology; Biochemistry; Platelet-derived growth factor receptor; Mathematics; Growth factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001251448,0.0002537206,0.0002405224,0.000101043,0.000101394,0.0002683139,0.0001708744,0.0002085794,0.0006706319],"category_scores_gemma":[0.000137744,0.0001679758,0.000289807,0.00008006525,0.0001675589,0.0001416123,0.000327998,0.0003780244,0.000385079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003223089,"about_ca_system_score_gemma":0.0002258714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004196355,"about_ca_topic_score_gemma":0.0006858844,"domain_scores_codex":[0.9998454,0.00002215402,0.00003353901,0.00002220699,0.0000400313,0.0000366391],"domain_scores_gemma":[0.9998189,0.00002337131,0.00005838006,0.00001946207,0.00001554772,0.00006440537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005706894,0.000009553189,0.0001432316,0.00001410489,0.000002885057,0.00004383158,0.000004107329,0.00003998381,0.9993072,0.00005270097,0.00001418018,0.0003112599],"study_design_scores_gemma":[0.00001301572,0.00007966381,0.01221743,0.00000747213,0.00001090954,0.0003550206,0.00002046609,0.001420555,0.9841589,0.00003469557,0.00167682,0.00000507338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964687,0.0004765556,0.002115365,0.00004510425,0.00001864454,0.00002336109,0.0002035556,0.00003744969,0.0006113527],"genre_scores_gemma":[0.9974883,0.0001840272,0.001068836,0.00003822258,0.000002833609,0.00001912886,0.0003638421,0.00001306213,0.0008217349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006706319,"threshold_uncertainty_score":0.002338529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07502901619139375,"score_gpt":0.3004642632360433,"score_spread":0.2254352470446496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}