{"id":"W1975043141","doi":"10.1016/j.jmb.2015.03.006","title":"Mitochondrial Genome Maintenance 1 (Mgm1) Protein Alters Membrane Topology and Promotes Local Membrane Bending","year":2015,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian HIV Trials Network, Canadian Institutes of Health Research; Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Academia Sinica","keywords":"Dynamin; Lipid bilayer fusion; Cell biology; Membrane; GTPase; mitochondrial fusion; Biology; Lipid bilayer; Membrane topology; Translocase of the inner membrane; Membrane protein; Biophysics; Chemistry; Inner mitochondrial membrane; Mitochondrion; Mitochondrial membrane transport protein; Biochemistry; Mitochondrial DNA; Cell; Endocytosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001910192,0.0002881151,0.0002059933,0.0001476702,0.0003904722,0.000348437,0.000372978,0.0006528296,0.00202972],"category_scores_gemma":[0.0003081156,0.0001754976,0.0002279731,0.0001311143,0.0003121286,0.0003693094,0.0005167755,0.0008120192,0.0006273644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004203576,"about_ca_system_score_gemma":0.0001481628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003076304,"about_ca_topic_score_gemma":0.0004339547,"domain_scores_codex":[0.9998527,0.00001940235,0.00001013198,0.00004587561,0.00003898648,0.00003294467],"domain_scores_gemma":[0.9998025,0.0000276297,0.00007754529,0.0000198222,0.00001847338,0.00005399226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002444062,0.00002310488,0.0006491328,0.00005090858,0.00000943817,0.0001259758,0.00001907072,0.00005709239,0.9971488,0.0002894711,0.0002376337,0.00114503],"study_design_scores_gemma":[0.00004322492,0.0001495376,0.01121109,0.00001022792,0.00002143175,0.0008243982,0.00008538039,0.001522445,0.9826869,0.0002579883,0.003179032,0.000008237883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949956,0.001103468,0.002413112,0.0004095818,0.0001085346,0.00000956806,0.0001708507,0.00009983697,0.0006894261],"genre_scores_gemma":[0.9980714,0.0001842413,0.0005261063,0.00007632725,0.000008834409,0.000007770521,0.0002136036,0.00001734735,0.0008944545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00202972,"threshold_uncertainty_score":0.006790102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01345312309599974,"score_gpt":0.2585494112431787,"score_spread":0.245096288147179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}