{"id":"W1975139962","doi":"10.1359/jbmr.2002.17.11.1977","title":"Effects of Liver-Derived Insulin-Like Growth Factor I on Bone Metabolism in Mice","year":2002,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; Novo Nordisk Fonden; Svenska Läkaresällskapet; Medical Research Council; Novo Nordisk; Stiftelsen för Strategisk Forskning","keywords":"Endocrinology; Internal medicine; Cortical bone; Bone remodeling; Insulin-like growth factor; Growth factor; Biology; Bone growth; Metabolism; Long bone; Genetically modified mouse; Chemistry; Transgene; Medicine; Receptor; Gene; Anatomy; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004464,0.001005039,0.0006589712,0.00135153,0.000301075,0.0006631801,0.0006715689,0.0008765002,0.001956704],"category_scores_gemma":[0.000234001,0.0006301539,0.0008970783,0.0005026977,0.0007785381,0.0003752386,0.000425103,0.00171417,0.0008190025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007440491,"about_ca_system_score_gemma":0.0005566921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001426478,"about_ca_topic_score_gemma":0.002169532,"domain_scores_codex":[0.9993826,0.00009101807,0.00007377534,0.0001948512,0.0001214165,0.0001363625],"domain_scores_gemma":[0.9992779,0.00009795967,0.0002690647,0.0000774678,0.00004666498,0.0002308632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001292371,0.0001808723,0.0003833194,0.00005738471,0.00001750349,0.0001051195,0.00002810874,0.0001221744,0.9959287,0.0001244791,0.00007680344,0.00168319],"study_design_scores_gemma":[0.0004558503,0.003136813,0.01117461,0.00004816408,0.0001507356,0.0004740554,0.000110428,0.001496618,0.9773419,0.0002055545,0.005367744,0.00003748884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834811,0.003732773,0.006186263,0.0004065622,0.0001565584,0.0001809832,0.003050278,0.0006873875,0.00211819],"genre_scores_gemma":[0.9654365,0.004584111,0.01110839,0.0005464595,0.00007121077,0.0008583088,0.004605541,0.0004015859,0.01238793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001956704,"threshold_uncertainty_score":0.006545842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04717195021605488,"score_gpt":0.3051531709709019,"score_spread":0.2579812207548471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}