{"id":"W1975242451","doi":"10.1016/j.tet.2011.07.088","title":"Preparation of chiral secondary boronic esters via copper-catalyzed enantioselective conjugate reduction of β-boronyl-β-alkyl α,β-unsaturated esters","year":2011,"lang":"en","type":"article","venue":"Tetrahedron","topic":"Organoboron and organosilicon chemistry","field":"Chemistry","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Enantioselective synthesis; Conjugate; Alkyl; Copper; Catalysis; Organic chemistry; Combinatorial chemistry; Hydride; Metal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001547124,0.000376797,0.0005336512,0.0001012803,0.00008130205,0.00001659137,0.0003334274,0.0003624625,0.001947338],"category_scores_gemma":[0.00004524612,0.0003884186,0.0001810777,0.0002885586,0.0003482521,0.0004108392,0.00006145623,0.0003777782,0.00002636096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002133942,"about_ca_system_score_gemma":0.0002813677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002862473,"about_ca_topic_score_gemma":0.00004045925,"domain_scores_codex":[0.9978678,0.00004363497,0.0007936298,0.0005579612,0.0003134295,0.0004235828],"domain_scores_gemma":[0.9984055,0.00003726171,0.000602555,0.0006206562,0.0001911268,0.000142959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004791497,0.0002776171,0.002250727,0.0004137943,0.0001675064,0.000003983806,0.002382365,0.000005338661,0.9906668,0.00004096744,0.0001587828,0.003152945],"study_design_scores_gemma":[0.001605699,0.000164613,0.003764008,0.000111881,0.0001245293,0.0000537425,0.0008201937,0.0001054429,0.9927258,0.00009391542,0.00005698307,0.0003731696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888962,0.0003701325,0.00003211954,0.00002697832,0.0002545845,0.0001983748,0.0000754225,0.0001675762,0.009978648],"genre_scores_gemma":[0.9987685,0.00007051673,0.0002524491,0.0000149242,0.00008813326,0.00001641951,0.0002309335,0.00006366245,0.0004944287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009872369,"threshold_uncertainty_score":0.9998568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224661271424896,"score_gpt":0.2473770270013273,"score_spread":0.2351304142870783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}