{"id":"W1975263280","doi":"10.4161/cbt.5.1.2400","title":"Cancer-selective therapy of the future: Apoptin and its mechanism of action","year":2006,"lang":"en","type":"review","venue":"Cancer Biology & Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Cancer; Mechanism (biology); Cancer cell; Cancer research; Biology; Mechanism of action; Cancer therapy; Bioinformatics; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003613514,0.0004282511,0.00047609,0.0004467267,0.0002863442,0.0007993862,0.0003536691,0.0009668583,0.001779828],"category_scores_gemma":[0.0001921064,0.0001227835,0.0002967477,0.0002856239,0.0005303645,0.00127207,0.0004557367,0.001619944,0.000622776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000751305,"about_ca_system_score_gemma":0.0004295601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004325754,"about_ca_topic_score_gemma":0.0009013459,"domain_scores_codex":[0.9998844,0.00002585593,0.000008646822,0.00002545308,0.00003736593,0.00001826389],"domain_scores_gemma":[0.9999437,0.00002015934,0.000008957193,0.000003316631,0.00001573614,0.000008084559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004196246,0.0001651062,0.0006038907,0.01309166,0.0001015355,0.001114853,0.000419296,0.001149133,0.1810685,0.09844337,0.03666378,0.6667594],"study_design_scores_gemma":[0.00002250001,0.0005579023,0.0008506129,0.0007024363,0.00005932187,0.003304623,0.0001144403,0.0004209944,0.03183482,0.008691747,0.9534163,0.00002419693],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003397241,0.9817885,0.004557588,0.003278002,0.001188073,0.00002907194,0.00004240031,0.00003675329,0.00568238],"genre_scores_gemma":[0.02408905,0.9590295,0.00313693,0.002586932,0.001164952,0.00004529736,0.00009987231,0.00001265887,0.009834738],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001779828,"threshold_uncertainty_score":0.005954087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05662188961185748,"score_gpt":0.392826461570645,"score_spread":0.3362045719587876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}