{"id":"W1975294257","doi":"10.1016/j.jneumeth.2012.03.012","title":"A new method of quantitatively assessing the opening of the blood–brain barrier in murine animal models","year":2012,"lang":"en","type":"article","venue":"Journal of Neuroscience Methods","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital de l'Enfant-Jésus; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Staining; Blood–brain barrier; Albumin; Mannitol; Andrology; Immunohistochemistry; Pathology; Chemistry; Biology; Endocrinology; Medicine; Biochemistry; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.006071271,0.0001645636,0.0004554023,0.0002142982,0.0002432406,0.00006038292,0.0008988964,0.00004594224,0.00001077794],"category_scores_gemma":[0.008706035,0.00008475454,0.0002012771,0.001553972,0.0004369015,0.001253727,0.0003103864,0.0005367157,1.043142e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000164003,"about_ca_system_score_gemma":0.0002292608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002182986,"about_ca_topic_score_gemma":0.000001248248,"domain_scores_codex":[0.9952039,0.00273127,0.0008115582,0.0002212932,0.0006904411,0.000341578],"domain_scores_gemma":[0.9955447,0.002780816,0.001142155,0.0002798997,0.0001301164,0.0001222885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003451956,0.00003552055,0.002437315,0.000009493901,0.000004046179,0.000002979528,0.002478899,0.0007311145,0.9843342,0.003668095,0.00005411239,0.006209719],"study_design_scores_gemma":[0.0005675128,0.0002921942,0.07973146,0.00007623996,0.00006979632,0.0005180015,0.0008943208,0.005368393,0.9076261,0.003269842,0.001447771,0.0001383833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4190854,0.00031798,0.5767365,0.001465527,0.001583312,0.0001587079,0.000003517121,0.000005054668,0.0006439977],"genre_scores_gemma":[0.7815326,0.00002407548,0.217406,0.0008145061,0.00008897633,0.000001252252,4.425518e-9,0.00001043658,0.0001221514],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.3624472,"threshold_uncertainty_score":0.999644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1705866976817127,"score_gpt":0.4706502325283657,"score_spread":0.3000635348466529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}