{"id":"W1975330797","doi":"10.1016/s0734-9750(03)00104-6","title":"Emerging trends in the synthesis and improvement of hapten-specific recombinant antibodies","year":2003,"lang":"en","type":"review","venue":"Biotechnology Advances","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Hapten; Phage display; Antibody; Polyclonal antibodies; Immunoassay; Monoclonal antibody; Recombinant DNA; Computational biology; Biology; Molecular biology; Immunology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004528321,0.000347882,0.001565136,0.0008493622,0.00009353882,0.000008964066,0.000313648,0.0004529107,0.00006862738],"category_scores_gemma":[0.0000890997,0.0001906494,0.000248248,0.0007106214,0.0006601346,0.00004479837,0.0001199546,0.0006876766,0.00000714878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003841857,"about_ca_system_score_gemma":0.00004616228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002550735,"about_ca_topic_score_gemma":0.00002116653,"domain_scores_codex":[0.9981626,0.0001010722,0.0006318797,0.0004618826,0.0002509193,0.0003916164],"domain_scores_gemma":[0.9988263,0.0003931503,0.0002689133,0.0004418785,0.00003191142,0.00003782297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002394815,0.0001041435,0.00006365214,0.004413025,0.00008976259,0.00006821397,0.00002166091,1.964538e-8,0.00005058001,0.003074198,0.0001829833,0.9919078],"study_design_scores_gemma":[0.0001510462,0.0002976581,0.0000603376,0.003957193,0.000149064,0.0002136613,0.0001591077,7.327524e-7,0.0004047753,0.0002364563,0.99419,0.0001799018],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004890842,0.9961147,0.000004598477,0.001590896,0.0001515266,0.00040409,0.0000269122,0.00002548031,0.001192661],"genre_scores_gemma":[0.0002147086,0.998501,0.0004948656,0.00003000001,0.00003287049,0.0001060718,0.00001826009,0.00002193956,0.0005802565],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9940071,"threshold_uncertainty_score":0.7774458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04811352344743488,"score_gpt":0.366179980174904,"score_spread":0.3180664567274691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}