{"id":"W1975408970","doi":"10.1074/jbc.m207883200","title":"Cell Detachment Triggers p38 Mitogen-activated Protein Kinase-dependent Overexpression of Fas Ligand","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; Health Sciences Centre","funders":"National Cancer Institute","keywords":"Anoikis; Cell biology; Extracellular matrix; Apoptosis; Biology; Programmed cell death; Protein kinase A; Basement membrane; Chemistry; Kinase; Cancer research; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001028027,0.0003172395,0.0001697531,0.0001684156,0.000165149,0.0002533935,0.0001392291,0.0002159566,0.001570004],"category_scores_gemma":[0.0001055586,0.0001126054,0.0002209311,0.0001507858,0.0001489538,0.0001677001,0.0002124095,0.0006836685,0.0002779462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003752872,"about_ca_system_score_gemma":0.0002655068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004986908,"about_ca_topic_score_gemma":0.0007077631,"domain_scores_codex":[0.9997972,0.0000236087,0.0000198142,0.00002992739,0.00006338814,0.00006616774],"domain_scores_gemma":[0.9999186,0.00001966123,0.0000161217,0.00001020692,0.000008757277,0.00002680164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001938656,0.00005977363,0.000134715,0.00005664047,0.000005534415,0.0001236644,0.00002815222,0.00005433266,0.9981459,0.0001197921,0.00007194888,0.001005723],"study_design_scores_gemma":[0.00006519384,0.0004884411,0.005779259,0.000009764804,0.00001401839,0.0003632645,0.00007440139,0.002147486,0.9878407,0.00008631585,0.003125515,0.000005587511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941435,0.001683463,0.001669929,0.0001846112,0.0000799039,0.00003451556,0.0002221037,0.00004877032,0.001933187],"genre_scores_gemma":[0.9938008,0.000977297,0.001576223,0.00005927891,0.0000165314,0.00004100386,0.0004739331,0.000004150653,0.003050752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001570004,"threshold_uncertainty_score":0.005252242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0172777512123172,"score_gpt":0.2275774475817619,"score_spread":0.2102996963694447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}